Dr. de Cabo is a Senior Investigator at the Translational Gerontology Branch, National Institute of Aging, Baltimore, MD. He is the head of the Aging, Metabolism, and Nutrition Unit (AMNU) at NIA. His research applies both physiological and tissue-specific molecular approaches to investigate effects of nutritional interventions on basic mechanisms of aging and age-related diseases. Research within his unit strives to identify protective mechanisms invoked by caloric restriction and to evaluate the consequences of dietary interventions on lifespan, pathology, and behavioral function. (tentative)