Wu Q, Klopack ET, Kim JK, Arpawong TE, Thyagarajan B, Cole S, Faul JD, Zhou F, Crimmins EM. Gene expression composite scores of cellular senescence predict aging health outcomes in the Health and Retirement Study. Nat Commun. In press. PMID: not yet assigned.
Sehgal R, Markov Y, Qin C, Meer M, Hadley C, Shadyab AH, Casanova R, Manson JE, Bhatti P, Moore AZ, Crimmins EM, Hagg S, Assimes TL, Whitsel EA, Higgins-Chen AT, Levine M. Systems Age: a single blood methylation test to quantify aging heterogeneity across 11 physiological systems. Nat Aging. 2025 Sep;5(9):1880-1896. doi:10.1038/s43587-025-00958-3. Epub 2025 Sep 15. PMID: 40954326.
Arpawong TE, Hernandez B, Potter C, Leigh RJ, Klopack ET, Hill C, Fiorito G, Smyth LJ, O’Halloran AM, McGuinness B, Faul JD, Kenny RA, McKnight AJ, Crimmins EM, McCrory C. Physiological health Age (PhysAge): a novel multi-system molecular timepiece predicts health and mortality in older adults. Geroscience. 2025 Sep 1. doi:10.1007/s11357-025-01832-1. Epub ahead of print. PMID: 40889076.
Crimmins EM. Life Expectancy and Health Expectancy in the Twenty-first Century: The Unthinkable, the Inconceivable, and the Unknowable. Demography. 2025 Aug 1;62(4):1217-1236. doi:10.1215/00703370-12185960. PMID: 40771033; NIHMSID: 2114317.
Brandhorst S, Levine M, Wei M, Shelehchi M, Morgan T, Nayak K, Dorff T, Hong K, Crimmins EM, Cohen P, Longo V. Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk. Nat Commun. 2024;15:1309. doi:10.1038/s41467-024-45260-9. PMID: 38341922; PMCID: PMC10879164.
Ramos CM, Curran SP. Comparative analysis of the molecular and physiological consequences of constitutive SKN-1 activation. Geroscience. 2023 Dec;45(6):3359-3370. doi:10.1007/s11357-023-00937-9. Epub 2023 Sep 26. PMID: 37751046; PMCID: PMC10643742.
Wang S, Prizment A, Moshele P, Vivek S, Blaes AH, Nelson HH, Thyagarajan B. Aging measures and cancer: Findings from the Health and Retirement Study. medRxiv [Preprint]. 2023 Sep 23:2023.09.20.23295845. doi:10.1101/2023.09.20.23295845. PMCID: PMC10543046. PMID: not assigned (preprint).
DeVito LM, Barzilai N, Cuervo AM, Niedernhofer LJ, Milman S, Levine M, Promislow D, Ferrucci L, Kuchel GA, Mannick J, Justice J, Gonzales MM, Kirkland JL, Cohen P, Campisi J. Extending human healthspan and longevity: a symposium report. Ann N Y Acad Sci. 2022 Jan;1507(1):70-83. doi:10.1111/nyas.14681. Epub 2021 Sep 8. PMID: 34498278; PMCID: PMC10231756.
Crimmins EM. Social hallmarks of aging: Suggestions for geroscience research. Aging Res Rev. 2020 Aug 13:101136. doi:10.1016/j.arr.2020.101136. PMID: 32798671; PMCID: PMC7530044.
Analyses of DNAm
Sehgal R, Markov Y, Qin C, Meer M, Hadley C, Shadyab AH, Casanova R, Manson JE, Bhatti P, Moore AZ, Crimmins EM, Hagg S, Assimes TL, Whitsel EA, Higgins-Chen AT, Levine M. Systems Age: a single blood methylation test to quantify aging heterogeneity across 11 physiological systems. Nat Aging. 2025 Sep;5(9):1880-1896. doi:10.1038/s43587-025-00958-3. Epub 2025 Sep 15. PMID: 40954326.
Arpawong TE, Hernandez B, Potter C, Leigh RJ, Klopack ET, Hill C, Fiorito G, Smyth LJ, O’Halloran AM, McGuinness B, Faul JD, Kenny RA, McKnight AJ, Crimmins EM, McCrory C. Physiological health Age (PhysAge): a novel multi-system molecular timepiece predicts health and mortality in older adults. Geroscience. 2025 Sep 1. doi:10.1007/s11357-025-01832-1. Epub ahead of print. PMID: 40889076.
Crimmins EM, Hernandez B, Potter C, Kim JK, Higgins-Chen A, Kenny RA, O’Halloran AM, McGuinness B, Smyth LJ, Hill C, Fiorito G, Faul J, McKnight AJ, McCrory C. Epigenetic Clocks Relate to 4 Age-related Health Outcomes Similarly Across 3 Countries. J Gerontol A Biol Sci Med Sci. 2025 Jun 10;80(7):glaf036. doi:10.1093/gerona/glaf036. PMID: 40091605; PMCID: PMC12168442.
Klopack ET, Hernandez B, Potter C, Faul JD, Hill C, Smyth L, Mitchell C, McCrory C, Kenny RA, McKnight AJ, McGuinness B, Crimmins EM. Remarkable concordance in associations between epigenetic clocks and health behaviors across three countries. Soc Sci Med. 2025 Sep;381:118287. doi:10.1016/j.socscimed.2025.118287. Epub 2025 May 30. PMID: 40532495; PMCID: PMC12422063.
Reynolds A, Farina MP, Crimmins E. Does the southern health disadvantage extend to accelerated biological aging: evidence from the health and retirement study. J Gerontol B Psychol Sci Soc Sci. 2025 Aug 23;80(9):gbaf122. doi:10.1093/geronb/gbaf122. PMID: 40580468; PMCID: PMC12409411.
Meier HCS, Klopack ET, Farina MP, Hernandez B, Mitchell C, Faul JD, McCrory C, Kenny RA, Crimmins EM. A novel DNA methylation-based surrogate biomarker for chronic systemic inflammation (InfLaMeS): results from the Health and Retirement Study. medRxiv [Preprint]. 2024 Oct 15:2024.10.11.24315339. doi:10.1101/2024.10.11.24315339. PMID: 39484273; PMCID: PMC11527057.
Choi EY, Ailshire JA. Neighborhood Stressors and Epigenetic Age Acceleration Among Older Americans. J Gerontol B Psychol Sci Soc Sci. 2024 Dec 1;79(12):gbae176. doi:10.1093/geronb/gbae176. PMID: 39432567; PMCID: PMC11582398.
Farina MP, Klopack ET, Umberson D, Crimmins EM. The embodiment of parental death in early life through accelerated epigenetic aging: implications for understanding how parental death in early life shapes age-related health risk among older adults. Soc Sci Med Popul Health. 2024;26:101648. doi:10.1016/j.ssmph.2024.101648. eCollection 2024 Jun. PMID: 38596364; PMCID: PMC11002886.
Crimmins EM, Klopack ET, Kim JK. Generations of epigenetic clocks and their links to socioeconomic status in the Health and Retirement Study. Epigenomics. 2024;16(14):1031-1042. doi:10.1080/17501911.2024.2373682. Epub 2024 Jul 18. PMID: 39023350; PMCID: PMC11404624.
Klopack E, Crimmins E. Epigenetic aging helps explain differential resilience in older adults. Demography. 2024;61(4):1023-1041. doi:10.1215/00703370-11466635. PMID: 39012228; PMCID: PMC11485224.
Brown RL, Alegria KE, Hamlat E, Tomiyama AJ, Laraia B, Crimmins EM, Moffitt TE, Epel ES. Psychosocial disadvantage during childhood and midlife health. JAMA Netw Open. 2024;7(7):e2421841. doi:10.1001/jamanetworkopen.2024.21841. PMID: 39073819; PMCID: PMC11287423.
Andrasfay T, Crimmins EM. Occupational characteristics and epigenetic aging among older adults in the United States. J Gerontol A Biol Sci Med Sci. 2023;78(11):2094-2104. doi:10.1093/gerona/glad204. PMID: 37611145; PMCID: PMC10259313.
Arpawong TE, Klopack ET, Kim JK, Crimmins EM. ADHD genetic burden associates with older epigenetic age: Mediating roles of education, behavioral, and sociodemographic factors among older adults. Clin Epigenetics. 2023;15:67. doi:10.1186/s13148-023-01367-4. PMCID: PMC10131361.
Klopack ET, Carroll JE, Cole SW, Seeman TE, Crimmins EM. Lifetime exposure to smoking, epigenetic aging, and morbidity and mortality in older adults. Clin Epigenetics. 2022;14:72. doi:10.1186/s13148-022-01286-8. PMCID: PMC9148451.
Klopack ET, Crimmins EM, Cole SW, Seeman TE, Carroll JE. Accelerated epigenetic aging mediates link between adverse childhood experiences and depressive symptoms in older adults: Results from the Health and Retirement Study. Soc Sci Med Popul Health. 2022;17:101071. doi:10.1016/j.ssmph.2022.101071. PMID: 35313610; PMCID: PMC8933834.
Crimmins EM, Thyagarajan B, Levine ME, Weir DR, Faul J. Associations of age, sex, race/ethnicity, and education with 13 epigenetic clocks in a nationally representative US sample: The Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2021;76(6):1117-1123. doi:10.1093/gerona/glab016. PMID: 33453106; PMCID: PMC8140049.
Faul JD, Kim JK, Levine ME, Thyagarajan B, Weir DR, Crimmins EM. Epigenetic-based age acceleration in a representative sample of older Americans: Associations with aging-related morbidity and mortality. Proc Natl Acad Sci U S A. 2023;120(8):e2301643119. doi:10.1073/pnas.2301643119. PMCID: PMC9992763.
Sugden K, Moffitt TE, Arpawong TE, Arseneault L, Belsky DW, Corcoran DL, Crimmins EM, Hannon E, Houts R, Mill JS, Poulton R, Ramrakha S, Wertz J, Williams BS, Caspi A. Cross-national and cross-generational evidence that educational attainment may slow the pace of aging in European-descent individuals. J Gerontol B Psychol Sci Soc Sci. 2023;78(11):2094-2104. doi:10.1093/geronb/gbad056. PMCID: PMC10394986.
Cappozzo A, McCrory C, Robinson O, Sterrantino AF, Sacerdote C, Krogh V, Panico S, Tumino R, Iacoviello L, Ricceri F, Sieri S, Chiodini P, McKay GJ, McKnight AJ, Neville C, Crimmins EM, Arpawong TE, Kenny RA, O’Halloran A, Polidoro S, Solinas G, Vineis P, Fiorito G. A blood DNA methylation biomarker for predicting short-term risk of cardiovascular events. Clin Epigenetics. 2022;14:121. doi:10.1186/s13148-022-01341-4. PMID: 36175966; PMCID: PMC9521011.
Rentscher KE, Klopack ET, Crimmins EM, Seeman TE, Cole SW, Carroll JE. Social relationships and epigenetic aging in older adulthood: Results from the Health and Retirement Study. Brain Behav Immun. 2023;114:349-359. doi:10.1016/j.bbi.2023.09.001. PMID: 37683960; PMCID: PMC10650967.
Kusters CDJ, Klopack ET, Crimmins EM, Seeman TE, Cole SW, Carroll JE. Short sleep and insomnia are associated with accelerated epigenetic age. Psychosom Med. 2023;85(8):782-789. doi:10.1097/PSY.0000000000001243. PMID: 37594243; PMCID: PMC10879461.
Kim JK, Arpawong TE, Klopack ET, Crimmins EM. Parental Divorce in Childhood and the Accelerated Epigenetic Aging for Earlier and Later Cohorts: Role of Mediators of Chronic Depressive Symptoms, Education, Smoking, Obesity, and Own Marital Disruption. J Popul Ageing. 2024 Jun;17(2):297-313. doi:10.1007/s12062-023-09434-5. Epub 2023 Oct 31. PMID: 39131698; PMCID: PMC11313353.
Sehgal R, Markov Y, Qin C, Meer M, Hadley C, Shadyab AH, Casanova R, Manson JE, Bhatti P, Crimmins EM, Hägg S, Assimes TL, Whitsel EA, Higgins-Chen AT, Levine M. Systems Age: A single blood methylation test to quantify aging heterogeneity across 11 physiological systems. bioRxiv [Preprint]. 2023 Jul 13:2023.07.13.548904. doi:10.1101/2023.07.13.548904. PMID: 37503069; PMCID: PMC10370047.
Mutambudzi M, Brown MT, Chen NW. Association of Epigenetic Age and Everyday Discrimination With Longitudinal Trajectories of Chronic Health Conditions in Older Adults. J Gerontol A Biol Sci Med Sci. 2024 Mar 1;79(3). doi:10.1093/gerona/glae005. PMID: 38190429; PMCID: PMC10878241.
Schmitz LL, Duffie E, Zhao W, Ratliff SM, Ding J, Liu Y, Merkin SS, Smith JA, Seeman T. Associations of Early-Life Adversity With Later-Life Epigenetic Aging Profiles in the Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol. 2023 Nov 10;192(12):1991-2005. doi:10.1093/aje/kwad172. PMID: 37579321; PMCID: PMC10988110.
Schmitz LL, Duque V. In utero exposure to the Great Depression is reflected in late-life epigenetic aging signatures. Proc Natl Acad Sci U S A. 2022 Nov 15;119(46):e2208530119. doi:10.1073/pnas.2208530119. Epub 2022 Nov 8. PMID: 36346848; PMCID: PMC9674255.
Schmitz LL, Zhao W, Ratliff SM, Goodwin J, Miao J, Lu Q, Guo X, Taylor KD, Ding J, Liu Y, Levine M, Smith JA. The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study. Epigenetics. 2022 Jun;17(6):589-611. doi:10.1080/15592294.2021.1939479. Epub 2021 Jul 6. PMID: 34227900; PMCID: PMC9235889.
Transcriptomics
Bather JR, Rodrigues M, Jiang Y, Cole SW, Cuevas AG. Neighborhood disadvantage and elevated CD14 gene expression among middle-aged adults: Findings from the Midlife in the United States study. Psychoneuroendocrinology. 2025 Oct;180:107553. doi:10.1016/j.psyneuen.2025.107553. Epub 2025 Jul 16. PMID: 40694969.
Boyle CC, Cole SW, Eisenberger NI, Olmstead R, Breen EC, Irwin MR. Sex differences in the transcriptional response to acute inflammatory challenge: results from a randomized endotoxin trial. Brain Behav Immun Health. 2024 Oct;40:100840. doi: 10.1016/j.bbih.2024.100840. PMID: 39252981; PMCID: PMC11381881.
Ricon-Becker I, West TN, Fredrickson BL, Kaplan DM, Mehl MR, Raison CL, Cole SW. Predicting psychosocial intervention response from baseline gene expression. Brain Behav Immun. 2024 Oct;121:331-339. doi: 10.1016/j.bbi.2024.08.004. Epub 2024 Aug 2. PMID: 39098435.
Kuhlmann KR, Cole SW, Tan EN, Swanson JA, Rao U. Childhood maltreatment and immune cell gene regulation during adolescence: Transcriptomics highlight non-classical monocytes. Biomolecules. 2024 Feb 13;14(2):220. doi: 10.3390/biom14020220. PMID: 38397457; PMCID: PMC10878094.
Ravi S, Shanahan MJ, Levitt B, Harris KM, Cole SW. Socioeconomic inequalities in early adulthood disrupt the immune transcriptomic landscape via upstream regulators. Sci Rep. 2024 Jan 13;14(1):1255. doi: 10.1038/s41598-024-51517-6. PMID: 38218990; PMCID: PMC10796907.
Apsley AT, Lee SA, Bhat AC, Rush J, Almeida DM, Cole SW, Shalev I. Affective reactivity to daily stressors and immune cell gene expression in the MIDUS study. Brain Behav Immun. 2024 Jan;115:80-88. doi: 10.1016/j.bbi.2023.09.025. Epub 2023 Oct 3. PMID: 37797778; PMCID: PMC10736901.
Klopack ET, Seshadri G, Arpawong TE, Cole S, Thyagarajan B, Crimmins EM. Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA). medRxiv [Preprint]. 2024 Dec 6:2024.12.04.24318517. doi:10.1101/2024.12.04.24318517. PMID: 39677460; PMCID: PMC11643192.
Wu Q, Klopack ET, Kim JK, Arpawong TE, Thyagarajan B, Cole S, Faul J, Crimmins EM. RNA-based indicators of cellular senescence predict aging health outcomes in the Health and Retirement Study. Nat Commun. Submitted, 2024. PMID: not assigned; PMCID: not assigned.
Walton KG, Wenuganen S, Cole SW. Transcendental Meditation practitioners show reduced expression of the Conserved Transcriptional Response to Adversity. Brain Behav Immun Health. 2023 Aug 2;32:100672. doi: 10.1016/j.bbih.2023.100672. eCollection 2023 Oct. PMID: 37560036; PMCID: PMC10529614.
Rahal D, Tashjian SM, Karan M, Eisenberger NI, Galván A, Fuligni AJ, Hastings PD, Cole SW. Positive and negative emotion are associated with generalized transcriptional activation in immune cells. Psychoneuroendocrinology. 2023 Jul;153:106103. doi: 10.1016/j.psyneuen.2023.106103. Epub 2023 Mar 29. PMID: 37054596; PMCID: PMC10332329.
Cuevas AG, Freilich CD, Mann FD, Cole SW, Krueger RF. Intersectional vulnerability in the relationship between discrimination and inflammatory gene expression. Brain Behav Immun Health. 2022 Dec 30;27:100580. doi: 10.1016/j.bbih.2022.100580. eCollection 2023 Feb. PMID: 36632340; PMCID: PMC9846859.
Snodgrass JG, Lacy MG, Dengah HJF 2nd, Polzer ER, Else RJ, Arevalo JMG, Cole SW. Positive mental well-being and immune transcriptional profiles in highly involved videogame players. Brain Behav Immun. 2019 Nov;82:84-92. doi:10.1016/j.bbi.2019.07.035. Epub 2019 Jul 31. PMID: 31376495; PMCID: PMC6800642.
Clinical Indicators
Sekher TV, Flood D, Green H, Hu P, Ali MK, Shete A, Pedgaonkar S, Langa KM, Crimmins EM, Bloom DE, Lee J. Prevalence, awareness, treatment, and control of diabetes in India: a nationally representative survey of adults aged 45 years and older. Lancet Glob Health. 2025 Sep;13(9):e1543–e1552. doi:10.1016/S2214-109X(23)00502-8. Epub 2025 Aug 7. PMID: 40784358; PMCID: PMC12397963.
Farina MP, Klopack ET, Crimmins EM. Using machine learning to identify differences in the association between blood-based biomarkers and later-life health across race and ethnicity. J Gerontol A Biol Sci Med Sci. 2025 Jul 24;80(8):glaf153. doi:10.1093/gerona/glaf153. PMID: 40680237; PMCID: PMC12360776.
Vivek S, Crimmins EM, Kim JK, Faul J, Jacobs DR, Guan W, Thyagarajan B. Impaired lung function is associated with elevated blood biomarkers of AD/ADRD: unraveling the interplay with risk of dementia. medRxiv [Preprint]. 2025 May 31:2025.05.29.25328529. doi:10.1101/2025.05.29.25328529. PMID: 40492085; PMCID: PMC12148282.
Lawton R, Frankenberg E, Suriastini NW, Seeman T, Karlamangla A, Friedman J. Cholesterol levels differ between older adults in Indonesia and the United States: The role of contextual and individual factors. Econ Hum Biol. 2024 Aug;54:101403. doi: 10.1016/j.ehb.2024.101403. PMID: 38861883; PMCID: PMC11330738.
Gruenewald T, Seeman TE, Choo TH, Scodes J, Snyder C, Pavlicova M, Weinstein M, Schwartz JE, Mukkamala R, Sloan RP. Cardiovascular variability, sociodemographics, and biomarkers of disease: the MIDUS study. Front Physiol. 2023 Aug 24;14:1234427. doi: 10.3389/fphys.2023.1234427. eCollection 2023. PMID: 37693005; PMCID: PMC10493187.
Zhao E, Ailshire JA, Kim JK, Wu Q, Crimmins EM. Associations between change in kidney functioning, age, and health indicators in the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2023;78(11):2094–2104. doi:10.1093/gerona/glad204. PMID: 37611145; PMCID: PMC10613000.
Mawhorter S, Crimmins EM, Ailshire JA. Housing and cardiometabolic risk among older renters and homeowners. Hous Stud. 2023;38(7):1342–1364. doi:10.1080/02673037.2021.1941792. Epub 2021 Jul 19. PMID: 37849684; PMCID: PMC10578645.
Inoue K, Seeman TE, Horwich T, Budoff MJ, Watson KE. Heterogeneity in the association between the presence of coronary artery calcium and cardiovascular events: A machine-learning approach in the MESA study. Circulation. 2023 Jan 10;147(2):132-141. doi: 10.1161/CIRCULATIONAHA.122.062626. Epub 2022 Oct 31. PMID: 36314118; PMCID: PMC9842312.
Burns SD, Baker EH, Sheehan CM. Disability and self-rated health: exploring foreign- and U.S.-born differences across adulthood. J Migr Health. 2022;6:100112. doi:10.1016/j.jmh.2022.100112. eCollection 2022. PMID: 35620793; PMCID: PMC9126965.
Wu Q, Ailshire JA, Kim JK, Crimmins EM. Cardiometabolic risk trajectory among older Americans: findings from the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2021;glab205. doi:10.1093/gerona/glab205. PMID: 34252185; PMCID: PMC8599082.
Kim JK, Crimmins EM. Blood pressure and mortality: joint effect of blood pressure measures. J Clin Cardiol Cardiovasc Ther. 2020;2(1):1009. doi:10.31546/2633-7916.1009. PMCID: PMC7646937.
Cobb RJ, Thorpe RJ, Norris KC. Everyday discrimination and kidney function among older adults: evidence from the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2020 Feb 14;75(3):517–521. doi:10.1093/gerona/glz294. PMID: 31838487; PMCID: PMC7021634.
Crimmins EM, Zhang YS, Kim JK, Levine ME. Changing disease prevalence, incidence, and mortality among older cohorts: the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2019 Nov 13;74(Suppl_1):S21–S26. doi:10.1093/gerona/glz075. PMID: 31724057; PMCID: PMC6853787.
Mitchell UA, Ailshire JA, Kim JK, Crimmins EM. Black–white differences in 20-year trends in cardiovascular risk in the United States, 1990–2010. Ethn Dis. 2019 Oct 17;29(4):587–598. doi:10.18865/ed.29.4.587. PMID: 31641326; PMCID: PMC6802170.
García C, Ailshire JA. Biological risk profiles among Latino subgroups in the Health and Retirement Study. Innov Aging. 2019 Jun 29;3(2):igz017. doi:10.1093/geroni/igz017. PMID: 31276052; PMCID: PMC6599425.
Donoho CJ, Seeman TE, Sloan RP, Crimmins EM, Kaslow NJ. Marital status, marital quality, and heart rate variability in the MIDUS cohort. J Fam Psychol. 2015;29(2):290–295. doi:10.1037/fam0000068. PMID: 25844496; PMCID: PMC4435975.
Papers on Methods
Dhankhar A, Khobragade P, Banerjee J, Chopra G, Jacob S, Dey AB, Lee J, Crimmins E, Thyagarajan B, Dey S, Hu P. Methodology of community-based venous blood specimen collection for the harmonized diagnostic assessment of dementia for the Longitudinal Aging Study in India (LASI-DAD): Wave 2. PLoS One. 2025 Jul 31;20(7):e0326917. doi:10.1371/journal.pone.0326917. PMID: 40743219; PMCID: PMC12312927.
Kim JK, Faul J, Weir DR, Crimmins EM. Dried blood spot–based biomarkers in the Health and Retirement Study: 2006 to 2016. Am J Hum Biol. 2024 Feb;36(2):e23997. doi:10.1002/ajhb.23997. Epub 2023 Oct 6. PMID: 37803815; PMCID: PMC10873048.
Farina M, Saenz J, Crimmins EM. Does adding MRI and CSF-based biomarkers improve cognitive status classification based on cognitive performance questionnaires? PLoS One. 2023 May 8;18(5):e0285220. doi:10.1371/journal.pone.0285220. eCollection 2023. PMID: 37155663; PMCID: PMC10166486.
McCrory C, McLoughlin S, Layte R, NiCheallaigh C, O’Halloran AM, Barros H, Berkman L, Bochud M, Crimmins E, Farrell M, Frag S, Grundy E, Kelly-Irving M, Petrovic D, Read S, Seeman T, Stringhini S, Vollenweider P, Kenny RA. Towards a consensus definition of allostatic load? A multi-cohort, multi-system, multi-biomarker individual participant data (IPD) meta-analysis. Psychoneuroendocrinology. 2023;153:106117. doi:10.1016/j.psyneuen.2023.106117. Epub 2023 Apr 19. PMID: 37100008; PMCID: PMC10620736.
Lee J, Petrosyan S, Khobragade P, Banerjee J, Chien S, Weerman B, Gross A, Hu P, Smith JA, Zhao W, Aksman L, Jain U, Shanthi GS, Kurup R, Raman A, Chakrabarti SS, Gambhir IS, Varghese M, John JP, Joshi H, Koul PA, Goswami D, Talukdar A, Mohanty RR, Yadati YSR, Padmaja M, Sankhe L, Rajguru C, Gupta M, Kumar G, Dhar M, Jovicich J, Ganna A, Ganguli M, Chatterjee P, Singhal S, Bansal R, Bajpai S, Desai G, Bhatankar S, Rao AR, Sivakumar PT, Muliyala KP, Sinha P, Loganathan S, Meijer E, Angrisani M, Kim JK, Dey S, Arokiasamy P, Bloom DE, Toga AW, Kardia SLR, Langa K, Crimmins EM, Dey AB. Deep phenotyping and genomic data from a nationally representative study on dementia in India. Sci Data. 2023 Jan 20;10(1):45. doi:10.1038/s41597-023-01941-6. PMID: 36670106; PMCID: PMC9852797.
Panikkar D, Vivek S, Crimmins E, Faul J, Langa KM, Thyagarajan B. Pre-analytical variables influencing stability of blood-based biomarkers of neuropathology. J Alzheimers Dis. 2023;95(2):735-748. doi:10.3233/JAD-230384. PMCID: PMC11520930.
Heiss JA, Bakulski KM, Thyagarajan B, Crimmins EM, Fisher J, Faul J, Just AC. Computational deconvolution of fifteen leukocyte subtypes from DNA methylation microarrays trained on flow cytometry data in the Health and Retirement Study. bioRxiv [Preprint]. 2023. PMID: not assigned; PMCID: not applicable (preprint).
Higgins-Chen AT, Thrush KL, Wang Y, Kuo P-L, Wang M, Minteer CJ, Moore AZ, Vinkers CH, Vermetten E, Rutten BPF, Geuze E, Okhuijsen-Pfeifer C, van der Horst MZ, Schreiter S, Gutwinski S, Luykx JJ, Ferrucci L, Crimmins EM, Boks MP, Hägg S, Hu-Seliger TT, Levine ME. A computational solution for bolstering reliability of epigenetic clocks: implications for clinical trials and longitudinal tracking. Nat Aging. 2022;2:644–661. doi:10.1038/s43587-022-00248-2. PMID: 36277076; PMCID: PMC9586209.
Crimmins EM, Thyagarajan B, Kim JK, Weir D, Faul J. Quest for a summary measure of biological age: the Health and Retirement Study. Geroscience. 2021;43(5):2405-2414. doi:10.1007/s11357-021-00325-1. PMID: 33544281; PMCID: PMC8050146.
Aguila E, Smith JP. Supplemental income program design: a cluster-randomized controlled trial to examine the health and wellbeing effects on older adults by gender, duration, and payment frequency. Soc Sci Med. 2020 Aug;259:113139. doi:10.1016/j.socscimed.2020.113139. Epub 2020 Jun 26. PMID: 32623230; PMCID: PMC7394009.
Zhang YS, Hu P, Strauss JA, Zhao Y, Wang Y, Crimmins EM. Ascertaining cause of mortality among middle-aged and older persons using computer-coded and expert review verbal autopsies in the China Health and Retirement Longitudinal Study. Glob Health Action. 2020 Dec 31;13(1):1768502. doi:10.1080/16549716.2020.1768502. PMID: 32544003; PMCID: PMC7480525.
Hunter-Schlichting D, Lane J, Cole B, Flaten Z, Barcelo H, Ramasubramanian R, Cassidy E, Faul J, Crimmins E, Pankratz N, Thyagarajan B. Validation of a hybrid approach to standardize immunophenotyping analysis in large population studies: the Health and Retirement Study. Sci Rep. 2020 May 29;10(1):8759. doi:10.1038/s41598-020-65016-x. PMCID: PMC7260195.
Crimmins EM, Zhang Y, Kim JK, Frochen S, Kang H, Shim H, Ailshire J, Potter A, Cofferen J, Faul J. Dried blood spots: effects of less than optimal collection, shipping time, heat, and humidity. Am J Hum Biol. 2020 Jan 10;32(4):e23390. doi:10.1002/ajhb.23390. PMCID: PMC7347424.
Haghani A, Miller B, Arpawong TE, Ailshire J. Integrating longitudinal population studies of aging in biological research. Methods Mol Biol. 2020;2144:259-273. doi:10.1007/978-1-0716-0592-9_23. PMID: 32410042.
Miller B, Haghani A, Ailshire J, Arpawong TE. Human population genetics in aging studies for molecular biologists. Methods Mol Biol. 2020;2144:67-76. doi:10.1007/978-1-0716-0592-9_6. PMID: 32410025.
Chen X, Crimmins E, Hu PP, Kim JK, Meng Q, Strauss J, Wang Y, Zeng J, Zhang Y, Zhao Y. Venous blood–based biomarkers in the China Health and Retirement Longitudinal Study: rationale, design, and results from the 2015 wave. Am J Epidemiol. 2019 Nov 1;188(11):1871-1877. doi:10.1093/aje/kwz170. PMID: 31364691; PMCID: PMC6825825.
Thomas D, Seeman T, Potter A, Hu P, Crimmins E, Herningtyas EH, Sumantri C, Frankenberg E. HPLC-based measurement of glycated hemoglobin using dried blood spots collected under adverse field conditions. Biodemography Soc Biol. 2018 Jan–Mar;64(1):43-62. doi:10.1080/19485565.2018.1451300. PMID: 29741414; PMCID: PMC6173327.
Thyagarajan B, Barcelo H, Crimmins E, Weir D, Minnerath S, Vivek S, Faul J. Effect of delayed cell processing and cryopreservation on immunophenotyping in multicenter population studies. J Immunol Methods. 2018 Dec;463:61-70. doi:10.1016/j.jim.2018.09.007. Epub 2018 Sep 14. PMID: 30222961; PMCID: PMC6423980.
Barcelo H, Faul J, Crimmins E, Thyagarajan B. A practical cryopreservation and staining protocol for immunophenotyping in population studies. Curr Protoc Cytom. 2018 Apr;84(1):e35. doi:10.1002/cpcy.35. PMID: 30040214; PMCID: PMC6060642.
Hu P, Edenfield M, Potter A, Kale V, Risbud A, Williams S, Lee J, Bloom DE, Crimmins E, Seeman T. Validation and modification of dried blood spot–based glycosylated hemoglobin assay for the Longitudinal Aging Study in India. Am J Hum Biol. 2015 Jul–Aug;27(4):579-581. doi:10.1002/ajhb.22664. Epub 2014 Dec 3. PMID: 25472916; PMCID: PMC4454625.
Hu P, Herningtyas EH, Kale V, Crimmins EM, Risbud AR, McCreath H, Lee J, Strauss J, O’Brien JC, Bloom DE, Seeman TE. External quality control for dried blood spot–based C-reactive protein assay: experience from the Indonesia Family Life Survey and the Longitudinal Aging Study in India. Biodemography Soc Biol. 2015;61(1):111-120. doi:10.1080/19485565.2014.1001886. PMID: 25879265; PMCID: PMC4410275.
Crimmins E, Kim JK, McCreath H, Faul J, Weir D, Seeman T. Validation of blood-based assays using dried blood spots for use in large population studies. Biodemography Soc Biol. 2014;60(1):38-48. doi:10.1080/19485565.2014.901885. PMID: 24784986; PMCID: PMC4117354.
Levine ME, Crimmins EM. A comparison of methods for assessing mortality risk. Am J Hum Biol. 2014 Nov–Dec;26(6):768-776. doi:10.1002/ajhb.22595. Epub 2014 Aug 4. PMID: 25088793; PMCID: PMC4286244.
Vasunilashorn, S., Best, L. E., Kim, J. K., Crimmins, E. M., Anson, J., Luy, M., Anson, J., & Luy, M. (2014). Predicting Mortality from Profiles of Biological Risk and Performance Measures of Functioning. In Mortality in an International Perspective (Vol. 18, pp. 119–135). Springer International Publishing AG. doi.org/10.1007/978-3-319-03029-6_5 (NHANES)
Crimmins, E. M., Vasunilashorn, S., Crimmins, E. M., & Rogers, R. G. (2011). Links Between Biomarkers and Mortality. In International Handbook of Adult Mortality (pp. 381–398). Springer Netherlands. doi.org/10.1007/978-90-481-9996-9_18 (NHANES and others)
Diet
Rahal D, Chiang JJ, Huynh VW, Bower JE, McCreath H, Fuligni AJ. Low subjective social status is associated with daily selection of fewer healthy foods and more high-fat/high-sugar foods. Appetite. 2023 Jan 1;180:106338. doi:10.1016/j.appet.2022.106338. Epub 2022 Oct 7. PMID: 36210016; PMCID: PMC10479967.
Choi YJ, Crimmins E, Ailshire J. Food insecurity, food environments, and disparities in diet quality and obesity in a nationally representative sample of community-dwelling older Americans. Prev Med Rep. 2022;29:101912. PMCID: PMC9326331.
Choi YJ, Ailshire J, Crimmins E. Diet quality and biological risk in a national sample of older Americans. J Aging Health. 2021 Nov 13;8982643211046818. doi:10.1177/08982643211046818. PMCID: PMC9098695.
Choi YJ, Crimmins E, Kim JK, Ailshire J. Food and nutrient intake and diet quality among older Americans. Public Health Nutr. 2021 May;24(7):1638–1647. doi:10.1017/S1368980021000430. PMID: 33557974; PMCID: PMC8094430.
Choi YJ, Ailshire JA, Crimmins EM. Living alone, social networks in neighbourhoods, and daily fruit and vegetable consumption among middle-aged and older adults in the USA. Public Health Nutr. 2020 Dec;23(18):3315–3323. doi:10.1017/S1368980020002475. Epub 2020 Aug 14. PMID: 32792025; PMCID: PMC7736134.
Levine ME, Suarez JA, Brandhorst S, Balasubramanian P, Cheng CW, Madia F, Fontana L, Mirisola MG, Guevara-Aguirre J, Wan J, Passarino G, Kennedy BK, Wei M, Cohen P, Crimmins EM, Longo VD. Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. Cell Metab. 2014 Mar 4;19(3):407–417. doi:10.1016/j.cmet.2014.02.006. PMID: 24606898; PMCID: PMC3988204.
Global Health
Burns SD, Ailshire JA, Crimmins EM. Functional limitation among middle-age and older adults: exploring cross-national gender disparities. Arch Gerontol Geriatr. 2024 Aug;123:105410. doi:10.1016/j.archger.2024.105410. Epub 2024 Mar 14. PMID: 38503129; PMCID: PMC11153036.
Burns SD, Crimmins EM, Zhang M, Ailshire JA. Psychosocial well-being differences between the young old, old-old, and oldest old: a global comparison. J Aging Health. 2024 Jul 20:8982643241264587. doi:10.1177/08982643241264587. Epub ahead of print. PMID: 39031083; PMCID: PMC11743824.
Osuna M, Farina M, Ailshire J. Disabled life expectancy among older Colombian men and women. PLoS One. 2024;19(1):e0296638. doi:10.1371/journal.pone.0296638. eCollection 2024. PMID: 38206966; PMCID: PMC10783758.
Burns SD, Best LE, Amoatey S. Exploring the intersectionality of place and gender among older adults in Ghana: an examination of women’s disability disadvantage. Innov Aging. 2024;8(4):igad134. doi:10.1093/geroni/igad134. eCollection 2024. PMID: 38572403; PMCID: PMC10986752.
Ailshire JA, Herrera CA, Choi E, Osuna M, Suzuki E. Cross-national differences in wealth inequality in health services and caregiving used near the end of life. EClinicalMedicine. 2023 Mar 16;58:101911. doi:10.1016/j.eclinm.2023.101911. PMID: 36969343; PMCID: PMC10030998.
Ailshire J, Osuna M, Wilkens J, Lee J. Family caregiving and place of death: insights from cross-national analysis of the harmonized end-of-life data. J Gerontol B Psychol Sci Soc Sci. 2021 Jun 8;76(Suppl 1):S76–S85. doi:10.1093/geronb/gbaa225. PMID: 33378449; PMCID: PMC8355452.
Ailshire J, Carr D. Cross-national comparisons of social and economic contexts of aging. J Gerontol B Psychol Sci Soc Sci. 2021 Jun 8;76(Suppl 1):S1–S4. doi:10.1093/geronb/gbab049. PMID: 34101809; PMCID: PMC8186853.
Saito Y, Kim JK, Davarian S, Hagedorn A, Crimmins EM. Cognitive performance among older persons in Japan and the United States. J Am Geriatr Soc. 2020 Feb;68(2):354–361. doi:10.1111/jgs.16163. Epub 2019 Sep 11. PMID: 31509240; PMCID: PMC7002215.
Zhang YS, Crimmins EM. Urban–rural differentials in age-related biological risk among middle-aged and older Chinese. Int J Public Health. 2019 Jul;64(6):831–839. doi:10.1007/s00038-018-1189-0. Epub 2018 Dec 8. PMID: 30535932; PMCID: PMC6556141.
Crimmins EM. Older persons in the Netherlands and the United States: similar in trends in life in good cognitive health and different in trends in life without disability/poor health. Am J Public Health. 2018;108(12):1582–1583. doi:10.2105/AJPH.2018.304759. PMID: 30403516; PMCID: PMC6236729.
Hu P, Wang S, Lee J. Socioeconomic gradients of cardiovascular risk factors in China and India: results from the China Health and Retirement Longitudinal Study and Longitudinal Aging Study in India. Int J Public Health. 2017 Sep;62(7):763–773. doi:10.1007/s00038-017-0968-3. Epub 2017 Apr 12. PMID: 28401249; PMCID: PMC5940550.
Wheaton FV, Crimmins EM. Female disability disadvantage: a global perspective on sex differences in physical function and disability. Ageing Soc. 2016 Jul;36(6):1136–1156. doi:10.1017/S0144686X15000227. Epub 2015 May 8. PMID: 27453613; PMCID: PMC4957517.
Crimmins EM. Physiological differences across populations reflecting early life and later life nutritional status and later life risk for chronic disease. J Popul Ageing. 2015 Mar;8(1–2):51–69. doi:10.1007/s12062-014-9109-4. PMID: 25750688; PMCID: PMC4346805.
Beltrán-Sánchez H, Crimmins EM, Teruel GM, Thomas D. Links between childhood and adult social circumstances and obesity and hypertension in the Mexican population. J Aging Health. 2011 Oct;23(7):1141–1165. doi:10.1177/0898264311422255. PMID: 21948773; PMCID: PMC3187563.
Beltrán-Sánchez H, Crimmins EM. Biological risk in the Mexican population at the turn of the 21st century. J Cross Cult Gerontol. 2013 Sep;28(3):299–316. doi:10.1007/s10823-013-9199-0. PMID: 23812952; PMCID: PMC3770809.
Vasunilashorn S, Kim JK, Crimmins EM. International differences in the links between obesity and physiological dysregulation: the United States, England, and Taiwan. J Obes. 2013;2013:618056. doi:10.1155/2013/618056. Epub 2013 May 28. PMID: 23781331; PMCID: PMC3679767.
Davarian S, Crimmins E, Takahashi A, Saito Y. Sociodemographic correlates of four indices of blood pressure and hypertension among older persons in Japan. Gerontology. 2013;59(5):392–400. doi:10.1159/000350531. Epub 2013 May 15. PMID: 23689609; PMCID: PMC3844551.
Crimmins EM, Wheaton F, Vasunilashorn S, Beltrán-Sánchez H, Zhang L, Kim JK. A global perspective on physiological change with age. In: Global Ageing in the Twenty-First Century: Challenges, Opportunities and Implications. Ashgate Publishing; 2013:79–103. (Book chapter; NHANES, CHARLS, SEBAS, ELSA, IFLS, JNHANES, ENSANUT, MxFLS, Tsimane). PMID: not applicable; PMCID: not applicable.
Vasunilashorn S, Kim JK, Crimmins EM, Winking J, Gurven M, Kaplan H, Finch CE. Blood lipids, infection, and inflammatory markers in the Tsimane of Bolivia. Am J Hum Biol. 2010 Nov–Dec;22(6):731–740. doi:10.1002/ajhb.21074. PMID: 20721985; PMCID: PMC3537506.
Gurven M, Kaplan H, Winking J, Eid Rodriguez D, Vasunilashorn S, Kim JK, Finch C, Crimmins E. Inflammation and infection do not promote arterial aging and cardiovascular disease risk factors among lean horticulturalists. PLoS One. 2009 Aug 11;4(8):e6590. doi:10.1371/journal.pone.0006590. PMID: 19668697; PMCID: PMC2722089.
Crimmins EM, Vasunilashorn S, Kim JK, Hagedorn A, Saito Y. A comparison of biological risk factors in two populations: the United States and Japan. Popul Dev Rev. 2008 Sep 5;34(3):457–482. doi:10.1111/j.1728-4457.2008.00232.x. PMID: 19421428; PMCID: PMC2676846.
COVID-19
Choi EY, Farina MP, Zhao E, Ailshire J. Changes in social lives and loneliness during COVID-19 among older adults: a closer look at sociodemographic differences. Int Psychogeriatr. 2023 Jun;35(6):305–317. doi:10.1017/S1041610222001107. Epub 2023 Jan 9. PMID: 36621851; PMCID: PMC10198802.
Farina MP, Ailshire JA. Sociodemographic and health status differences in delaying medical care during the COVID-19 pandemic among older adults: findings from the Health and Retirement Study. BMC Public Health. 2022 Sep 10;22(1):1720. doi:10.1186/s12889-022-14118-4. PMID: 36088320; PMCID: PMC9463671.
Lee H, Andrasfay T, Riley A, Wu Q, Crimmins EM. Do social determinants of health explain racial/ethnic disparities in COVID-19 infection? Soc Sci Med. 2022 Aug;306:115098. doi:10.1016/j.socscimed.2022.115098. Epub 2022 Jun 3. PMID: 35759973; PMCID: PMC9162789.
Wu Q, Ailshire JA, Crimmins EM. Long COVID and symptom trajectory in a representative sample of Americans in the first year of the pandemic. Sci Rep. 2022 Jul 8;12(1):11647. doi:10.1038/s41598-022-15727-0. PMID: 35804058; PMCID: PMC9264749.
Choi EY, Farina MP, Wu Q, Ailshire J. COVID-19 social distancing measures and loneliness among older adults. J Gerontol B Psychol Sci Soc Sci. 2022 Jul 5;77(7):e167–e178. doi:10.1093/geronb/gbab009. PMID: 33428753; PMCID: PMC7928665.
Cobb RJ, Sheehan CM, Nguyen AW, Johnson D. COVID-19 hardships and self-reported sleep quality among American adults in March and April 2020: results from a nationally representative panel study. Sleep Health. 2022 Jun;8(3):288–293. doi:10.1016/j.sleh.2022.01.001. Epub 2022 Apr 7. PMID: 35400616; PMCID: PMC8987572.
Andrasfay T, Wu Q, Lee H, Crimmins EM. Adherence to social-distancing and personal hygiene behavior guidelines and risk of COVID-19 diagnosis: evidence from the Understanding America Study. Am J Public Health. 2022 Jan;112(1):169–178. doi:10.2105/AJPH.2021.306565. PMID: 34936403; PMCID: PMC8713629.
Easterlin MC, Crimmins EM, Finch CE. Will prenatal exposure to SARS-CoV-2 define a birth cohort with accelerated aging in the century ahead? J Dev Orig Health Dis. 2021 Oct;12(5):683–687. doi:10.1017/S204017442000104X. Epub 2020 Nov 10. PMID: 33168125; PMCID: PMC7674789.
Cobb RJ, Erving CL, Byrd WC. Perceived COVID-19 health threat increases psychological distress among Black Americans. Ethn Racial Stud. 2021;44(5):806–818. doi:10.1080/01419870.2021.1867216. Epub 2021 Feb 3. PMID: 34035554; PMCID: PMC8143036.
Kim JK, Crimmins EM. Age differences in the relationship between threatening and coping mechanisms and preventive behaviors in the time of COVID-19 in the United States: Protection Motivation Theory. Res Psychother. 2020 Dec 31;23(3):485. doi:10.4081/ripppo.2020.485. eCollection 2020 Dec 31. PMID: 33585294; PMCID: PMC7876510.
Kim JK, Crimmins EM. How does age affect personal and social reactions to COVID-19? Results from the national Understanding America Study. PLoS One. 2020;15(11):e0241950. doi:10.1371/journal.pone.0241950. PMID: 33170903; PMCID: PMC7654776.
Zhao E, Wu Q, Crimmins EM, Ailshire JA. Media trust and infection mitigating behaviours during the COVID-19 pandemic in the USA. BMJ Glob Health. 2020 Oct;5(10):e003323. doi:10.1136/bmjgh-2020-003323. PMID: 33037063; PMCID: PMC7545496.
Crimmins EM. Age-related vulnerability to coronavirus disease 2019 (COVID-19): biological, contextual, and policy-related factors. Public Policy Aging Rep. 2020;30(4):142–146. doi:10.1093/ppar/praa023. Epub 2020 Sep 7. PMID: 33214754; PMCID: PMC7499698.
Contextual Analysis
Ailshire JA, Farina MP, Jackson H, Walsemann KM. The role of educational attainment and quality in U.S. regional variation in prevalence of dementia and CIND. PLoS One. 2025 Sep 18;20(9):e0332410. doi:10.1371/journal.pone.0332410. PMID: 40966257; PMCID: PMC12445459.
Fisk CE, Walsemann KM, Jones C, Crimmins E, Ailshire JA. Living in historically redlined neighborhoods and biological aging among older adults. J Gerontol A Biol Sci Med Sci. 2025 Sep 2:glaf190. doi:10.1093/gerona/glaf190. Epub ahead of print. PMID: 40891889.
Van Dang K, Choi EY, Crimmins E, Finch C, Ailshire J. The joint effects of exposure to ambient long-term air pollution and short-term heat on epigenetic aging in the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2025 Jun 10;80(7):glaf092. doi:10.1093/gerona/glaf092. PMID: 40326421; PMCID: PMC12287630.
Choi EY, Ailshire JA. Ambient outdoor heat and accelerated epigenetic aging among older adults in the US. Sci Adv. 2025 Feb 28;11(9):eadr0616. doi:10.1126/sciadv.adr0616. Epub 2025 Feb 26. PMID: 40009659; PMCID: PMC11864172.
Fisk CE, Ailshire JA, Walsemann KM. Living in historically redlined neighborhoods and the cognitive function of Black and White adults. J Aging Health. 2025 Jan 18:8982643251315020. doi:10.1177/08982643251315020. Epub ahead of print. PMID: 39825796; PMCID: PMC12271469.
Goel N, Hernandez A, Cole SW. Social genomic determinants of health: Neighborhood disadvantage and cancer outcomes. J Clin Oncol. 2024 Oct 20;42(30):3618-3627. doi:10.1200/JCO.23.02007. PMID: 39178356; PMCID: PMC12045328.
Ortiz R, Kershaw KN, Zhao S, Kline D, Brock G, Jaffee S, Golden SH, Ogedegbe G, Carroll J, Seeman TE, Joseph JJ. Evidence for the association between adverse childhood family environment, child abuse, and caregiver warmth and cardiovascular health across the lifespan: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Circ Cardiovasc Qual Outcomes. 2024 Feb;17(2):e009794. doi:10.1161/CIRCOUTCOMES.122.009794. Epub 2024 Jan 23. PMID: 38258561; PMCID: PMC11078262.
Ailshire JA, Finch CE. Recently decreased association of air pollution with cognitive impairment in a population-based aging cohort and in a mouse model. Alzheimers Dement. 2022 May;18(5):1077–1078. doi:10.1002/alz.12471. Epub 2021 Oct 7. PMID: 34617667; PMCID: PMC11703122.
Ailshire J, Walsemann KM. Education differences in the adverse impact of PM2.5 on incident cognitive impairment among U.S. older adults. J Alzheimers Dis. 2021;79(2):615–625. doi:10.3233/JAD-200765. PMID: 33337363; NIHMSID: 2031847.
Crimmins EM, Ailshire JA. Aging and place: the importance of place in aging. Public Policy Aging Rep. 2021;31(1):1–2. doi:10.1093/ppar/praa043. Epub 2020 Dec 24. PMID: 33859458; PMCID: PMC8046522.
Erving CL, Cobb RJ. Neighborhood social group participation and depressive symptoms among mid-to-late life Black Americans: does the association differ by ethnicity? J Immigr Minor Health. 2021 Jun;23(3):478–486. doi:10.1007/s10903-020-01070-x. PMID: 32816172; PMCID: PMC8018608.
Ailshire J, Brown LL. The importance of air quality policy for older adults and diverse communities. Public Policy Aging Rep. 2020 Dec 9;31(1):33–37. doi:10.1093/ppar/praa036. Erratum in: Public Policy Aging Rep. 2021 Apr 23;31(3):110. doi:10.1093/ppar/prab001. PMID: 33462554; PMCID: PMC7799383.
Besser L, Galvin JE, Rodriguez D, Seeman T, Kukull W, Rapp SR, Smith J. Associations between neighborhood built environment and cognition vary by apolipoprotein E genotype: Multi-Ethnic Study of Atherosclerosis. Health Place. 2019 Nov;60:102188. doi:10.1016/j.healthplace.2019.102188. Epub 2019 Nov 29. PMID: 31797769; PMCID: PMC6901106.
Frochen S, Ailshire J, Rodnyansky S. Residential care in Los Angeles: evaluating the spatial distribution of facilities and neighbourhood access to care among older adults. Local Environ. 2019;24(3):274–288. doi:10.1080/13549839.2018.1564254. Epub 2019 Jan 4. PMID: 33033440; PMCID: PMC7539763.
Lifecycle Health
Rahal D, Irwin MR, Fuligni AJ. Family meals are associated with lower substance use in female adolescents. Fam Process. 2024 Jul 31. doi:10.1111/famp.13039. Epub ahead of print. PMID: 39082079; PMCID: PMC11781996.
Walsemann KM, Fisk CE, Farina MP, Abbruzzi E, Ailshire JA. Race, gender, and cohort differences in the educational experiences of Black and White Americans. Popul Res Policy Rev. 2023 Dec;42(6):86. doi:10.1007/s11113-023-09831-w. Epub 2023 Oct 27. PMID: 39206094; PMCID: PMC11349311.
García C, Garcia MA, Ailshire JA. Demographic and health characteristics of older Latino birth cohorts in the Health and Retirement Study. J Gerontol B Psychol Sci Soc Sci. 2022 Nov 23;77(11):2060–2071. doi:10.1093/geronb/gbac017. PMID: 35092422; PMCID: PMC9683499.
Rocha S, Almeida DM, Chiang JJ, Cole SW, Irwin MR, Seeman T, Fuligni AJ. The relationship between family socioeconomic status and adolescent sleep and diurnal cortisol. Psychosom Med. 2022 Sep 1;84(7):848–855. doi:10.1097/PSY.0000000000001104. Epub 2022 Jun 29. PMID: 35797448; PMCID: PMC9437129.
Karan M, Bai S, Almeida DM, Irwin MR, McCreath H, Fuligni AJ. Sleep–wake timings in adolescence: chronotype development and associations with adjustment. J Youth Adolesc. 2021 Apr;50(4):628–640. doi:10.1007/s10964-021-01407-1. Epub 2021 Feb 19. PMID: 33606125; PMCID: PMC7993411.
Park H, Chiang JJ, Bower JE, Irwin MR, Almeida DM, Seeman TE, McCreath H, Fuligni AJ. Sleep and inflammation during adolescents’ transition to young adulthood. J Adolesc Health. 2020 Dec;67(6):821–828. doi:10.1016/j.jadohealth.2020.04.015. Epub 2020 Jun 23. PMID: 32586679; PMCID: PMC9869641.
Rahal D, Chiang JJ, Fales M, Fuligni AJ, Haselton MG, Slavich GM, Robles TF. Early life stress, subjective social status, and health during late adolescence. Psychol Health. 2020 Dec;35(12):1531–1549. doi:10.1080/08870446.2020.1761977. Epub 2020 May 13. PMID: 32400197; PMCID: PMC7666044.
Rahal D, Huynh V, Cole S, Seeman T, Fuligni A. Subjective social status and health during high school and young adulthood. Dev Psychol. 2020 Jun;56(6):1220–1232. doi:10.1037/dev0000919. Epub 2020 Mar 30. PMID: 32223295; PMCID: PMC7217753.
Chiang JJ, Cole SW, Bower JE, Irwin MR, Taylor SE, Arevalo J, Fuligni AJ. Depressive symptoms and immune transcriptional profiles in late adolescents. Brain Behav Immun. 2019 Aug;80:163–169. doi:10.1016/j.bbi.2019.03.004. Epub 2019 Mar 6. PMID: 30851376; PMCID: PMC6710012.
Park H, Chiang JJ, Irwin MR, Bower JE, McCreath H, Fuligni AJ. Developmental trends in sleep during adolescents’ transition to young adulthood. Sleep Med. 2019 Aug;60:202–210. doi:10.1016/j.sleep.2019.04.007. Epub 2019 Apr 19. PMID: 31186213; PMCID: PMC6650269.
Chiang JJ, Cole SW, Bower JE, Irwin MR, Taylor SE, Arevalo J, Fuligni AJ. Daily interpersonal stress, sleep duration, and gene regulation during late adolescence. Psychoneuroendocrinology. 2019 May;103:147–155. doi:10.1016/j.psyneuen.2018.11.026. Epub 2018 Dec 28. PMID: 30690224; PMCID: PMC8447850.
Socioeconomic Status and Mortality
Noghanibehambari H, Fletcher J, Schmitz L, Duque V, Gawai V. Early-life economic conditions and old-age male mortality: evidence from historical county-level bank deposit data. J Popul Econ. 2024 Mar;37(1). doi:10.1007/s00148-024-01007-w. Epub 2024 Feb 29. PMID: 39301052; PMCID: PMC11411638.
Zhang YS, Strauss JA, Hu P, Zhao Y, Crimmins EM. Links between mortality and socioeconomic characteristics, disease burden, and biological and physical functioning in the aging Chinese population. J Gerontol B Psychol Sci Soc Sci. 2022 Feb 3;77(2):365–377. doi:10.1093/geronb/gbab059. PMID: 33837409; PMCID: PMC8824635.
Cobb RJ, Sheehan CM, Louie P, Erving CL. Multiple reasons for perceived everyday discrimination and all-cause mortality risk among older Black adults. J Gerontol A Biol Sci Med Sci. 2022 Feb 3;77(2):310–314. doi:10.1093/gerona/glab281. PMID: 34605539; PMCID: PMC9012980.
Sudharsanan N, Zhang Y, Payne CF, Dow W, Crimmins E. Education and adult mortality in middle-income countries: surprising gradients in six nationally representative longitudinal surveys. SSM Popul Health. 2020 Dec;12:100649. doi:10.1016/j.ssmph.2020.100649. eCollection 2020 Dec. PMID: 32923576; PMCID: PMC7475202.
Stewart QT, Cobb RJ, Keith VM. The color of death: race, observed skin tone, and all-cause mortality in the United States. Ethn Health. 2020 Oct;25(7):1018–1040. doi:10.1080/13557858.2018.1469735. Epub 2018 May 8. PMID: 29737188; PMCID: PMC6222008.
Sex Differences
Kim JK, Crimmins EM. Early menopause, hysterectomy, and biological aging: Health and Retirement Study. Menopause. 2025 Aug 1;32(8):692-701. doi:10.1097/GME.0000000000002555. PMID: 40460368; PMCID: PMC12236146.
Kerr EM, Ailshire JA, Crimmins E, Walsemann KM. Sex variation in the relationship between APOE ε4, cognitive decline, and dementia. Alzheimers Dement (Amst). 2025 May 2;17(2):e70053. doi:10.1002/dad2.70053. PMID: 40322470; PMCID: PMC12047073.
Resciniti NV, Farina MP, Merchant AT, Lohman MC. Depressive symptoms partially mediate the association of frailty phenotype symptoms and cognition for females but not males. J Aging Health. 2023 Jan;35(1-2):42-49. doi:10.1177/08982643221100688. Epub 2022 May 8. PMID: 35527693; PMCID: PMC9640765.
Zhao E, Crimmins EM. Mortality and morbidity in ageing men: biology, lifestyle and environment. Rev Endocr Metab Disord. 2022 Dec;23(6):1285-1304. doi:10.1007/s11154-022-09737-6. Epub 2022 Jun 14. PMID: 35697963; PMCID: PMC9748037.
Haghani A, Arpawong TE, Kim JK, Lewinger JP, Finch CE, Crimmins E. Female vulnerability to the effects of smoking on health outcomes in older people. PLoS One. 2020;15(6):e0234015. doi:10.1371/journal.pone.0234015. PMID: 32497122; PMCID: PMC7272024.
Kim JK, Ailshire JA, Crimmins EM. Twenty-year trends in cardiovascular risk among men and women in the United States. Aging Clin Exp Res. 2019 Jan;31(1):135-143. doi:10.1007/s40520-018-0932-y. Epub 2018 Mar 22. PMID: 29569117; PMCID: PMC6151160.
Stress and Psychological and Mental Health
Hansen JL, Carroll JE, Seeman TE, Cole SW, Rentscher KE. Lifetime chronic stress exposures, stress hormones, and biological aging: results from the Midlife in the United States (MIDUS) study. Brain Behav Immun. 2025 Jan;123:1159–1168. doi:10.1016/j.bbi.2024.10.022. Epub 2024 Oct 22. PMID: 39442637; PMCID: PMC11874905.
Choi YJ, Choi EY, Ailshire JA. Neighborhood poverty and hopelessness in older adults: the mediating role of perceived neighborhood disorder. PLoS One. 2024 Oct 15;19(10):e0311894. doi:10.1371/journal.pone.0311894. PMCID: PMC11478814.
Choi YJ, Ailshire JA. Perceived neighborhood disorder, social cohesion, and depressive symptoms in spousal caregivers. Aging Ment Health. 2024 Jan–Feb;28(1):54–61. doi:10.1080/13607863.2023.2212250. Epub 2023 May 25. PMID: 37227056; PMCID: PMC12459910.
Lawton R, Frankenberg E, Seeman T, Crimmins E, Sumantri C, Thomas D. Exposure to the Indian Ocean tsunami shapes the HPA axis resulting in HPA “burnout” 14 years later. Proc Natl Acad Sci U S A. 2023 Oct 31;120(44):e2306497120. doi:10.1073/pnas.2306497120. Epub 2023 Oct 16. PMID: 37844215; PMCID: PMC10622908.
Choi EY, Zelinski EM, Ailshire J. Neighborhood social environment and self-perceptions of aging. Innov Aging. 2023 Apr 27;7(4):igad038. doi:10.1093/geroni/igad038. PMID: 37213322; PMCID: PMC10195563.
Arpawong TE, Sakuma KK, Espinoza L, Huh J. Longitudinal examination of an ethnic paradox of stress and mental health in older Black and Latinx adults. Clin Gerontol. 2023 Jan–Feb;46(1):27–46. doi:10.1080/07317115.2022.2056102. Epub 2022 Mar 23. PMID: 35320059; PMCID: PMC9500116.
Karlamangla AS, Almeida DM, Lachman ME, Merkin SS, Thomas D, Seeman TE. Diurnal dynamic range as index of dysregulation of system dynamics: a cortisol exemplar using data from the Study of Midlife in the United States. Psychoneuroendocrinology. 2022 Aug;142:105804. doi:10.1016/j.psyneuen.2022.105804. Epub 2022 May 17. PMID: 35623318; PMCID: PMC9262344.
Arpawong TE, Mekli K, Lee J, Phillips DF, Gatz M, Prescott CA. A longitudinal study shows stress proliferation effects from early childhood adversity and recent stress on risk for depressive symptoms among older adults. Aging Ment Health. 2022 Apr;26(4):870–880. doi:10.1080/13607863.2021.1904379. Epub 2021 Mar 30. PMID: 33784211; PMCID: PMC8673399.
Snodgrass JG, Lacy MG, Cole SW. Internet gaming, embodied distress, and psychosocial well-being: a syndemic-syndaimonic continuum. Soc Sci Med. 2022 Feb;295:112728. doi:10.1016/j.socscimed.2019.112728. Epub 2019 Dec 12. PMID: 31879045; PMCID: PMC7289667.
Lincoln KD, Ailshire J, Nguyen A, Taylor RJ, Govia I, Ifatunji MA. Profiles of sleep and depression risk among Caribbean Blacks. Ethn Health. 2021 Oct;26(7):981–999. doi:10.1080/13557858.2019.1620179. Epub 2019 May 28. PMID: 31137946; PMCID: PMC6881538.
Walsemann KM, Ailshire JA, Hartnett CS. The other student debt crisis: how borrowing to pay for a child’s college education relates to parents’ mental health at midlife. J Gerontol B Psychol Sci Soc Sci. 2020 Aug 13;75(7):1494–1503. doi:10.1093/geronb/gbz146. PMID: 31696915; PMCID: PMC7424281.
Thorpe RJ Jr, Cobb R, King K, Bruce MA, Archibald P, Jones HP, Norris KC, Whitfield KE, Hudson D. The association between depressive symptoms and accumulation of stress among Black men in the Health and Retirement Study. Innov Aging. 2020;4(5):igaa047. doi:10.1093/geroni/igaa047. eCollection 2020. PMID: 33354627; PMCID: PMC7737789.
Brown LL, Mitchell UA, Ailshire JA. Disentangling the stress process: race/ethnic differences in the exposure and appraisal of chronic stressors among older adults. J Gerontol B Psychol Sci Soc Sci. 2020 Feb 14;75(3):650–660. doi:10.1093/geronb/gby072. PMID: 29878196; PMCID: PMC7328036.
Biological Age
Freilich DC, Mann FD, Markon KE, Cole SW, Krueger RF. Predicting epigenetic aging by the transdiagnostic internalizing spectrum vs. depressive and anxiety syndromes. World Psychiatry. 2025 Oct;24(3):448-450. doi: 10.1002/wps.21364. PMID: 40948069; PMCID: PMC11885677.
Cuevas AG, Bather JR, Kranz E, Zhang X, Cole SW. Neighborhood Opportunity and Biological Aging: Results From the Midlife in the United States. Biopsychosoc Med. 2025 Oct 1;87(8):520-528. doi: 10.1097/PSY.0000000000001419. Epub 2025 Jul 14. PMID: 40996216.
Farina MP, Kim JK, Crimmins EM. Increasing Educational Inequality in Biological Aging Among U.S. Adults Aged 50–79 From 1988–1994 to 2015–2018. Demography. 2025 Aug 1;62(4):1367-1388. doi:10.1215/00703370-12175545. PMID: 40739980; NIHMSID: 2103859.
Hansen JL, Carroll JE, Seeman TE, Cole SW, Rentscher KE. Lifetime chronic stress exposures, stress hormones, and biological aging: Results from the Midlife in the United States (MIDUS) study. Brain Behav Immun. 2025 Jan;123:1159-1168. doi: 10.1016/j.bbi.2024.10.022. Epub 2024 Oct 22. PMID: 39442637; PMCID: PMC11874905.
Freilich CD, Markon KE, Mann FD, Cole SW, Krueger RF. Associations between loneliness, epigenetic aging, and multimorbidity through older adulthood. J Gerontol B Psychol Sci Soc Sci. 2024 Dec 7;79(12):gbae169. doi: 10.1093/geronb/gbae169. PMID: 39417537.
Freilich CD, Markon KE, Cole SW, Krueger RF. Loneliness, epigenetic age acceleration, and chronic health conditions. Psychol Aging. 2024 Jun;39(4):337-349. doi: 10.1037/pag0000822. Epub 2024 Apr 18. PMID: 38635160; PMCID: PMC11247453.
Cuevas AG, Cole SW, Belsky DW, McSorley AM, Shon JM, Chang VW. Multi-discrimination exposure and biological aging: Results from the midlife in the United States study. Brain Behav Immun Health. 2024 May 9;39:100774. Doi: 10.1016/j.bbih.2024.100774. eCollection 2024 Aug. PMID: 39132086.
Kim ES, Nakamura JS, Strecher VJ, Cole SW. Reduced epigenetic age in older adults with high sense of purpose in life. J Gerontol A Biol Sci Med Sci. 2023 Jul 8;78(7):1092-1099. doi: 10.1093/gerona/glad092. PMID: 36966357; PMCID: PMC10378693.
Nakamura JS, Kwok C, Huang A, Strecher VJ, Kim ES, Cole SW. Reduced epigenetic age in older adults who volunteer. Psychoneuroendocrinology. 2023 Feb;148:106000. doi: 10.1016/j.psyneuen.2022.106000. Epub 2022 Dec 8. PMID: 36521251.
Andrasfay T, Kim JK, Ailshire J, Crimmins EM. Aging on the job? The association between occupational characteristics and accelerated biological aging. J Gerontol B Psychol Sci Soc Sci. 2023;gbad055. doi:10.1093/geronb/gbad055. PMCID: PMC10292835.
Wu AH, Setiawan VW, Stram DO, Crimmins EM, Tseng CC, Lim U, Park SY, White KK, Cheng I, Haiman C, Wilkens LR, Le Marchand L. Racial, ethnic, and socioeconomic differences in a deficit accumulation frailty index in the Multiethnic Cohort Study. J Gerontol A Biol Sci Med Sci. 2023;78(7):1246-1257. doi:10.1093/gerona/glac216. PMID: 36255109; PMCID: PMC11255091.
Farina M, Kim JK, Crimmins EM. Racial/ethnic differences in biological aging and their life course socioeconomic determinants: The 2016 Health and Retirement Study. J Aging Health. 2023;35(3-4):209-220. doi:10.1177/08982643221120743. Epub 2022 Aug 19. PMID: 35984401; PMCID: PMC9898094.
Cao X, Ma C, Zheng Z, He L, Hao M, Chen X, Crimmins EM, Gill TM, Levine ME, Liu Z. Contribution of life course circumstances to the acceleration of phenotypic and functional aging: A retrospective study. E Clin Med. 2022;51:101548. doi:10.1016/j.eclinm.2022.101548. PMID: 35844770; PMCID: PMC9284373.
Thomas Tobin CS, Gutiérrez Á, Bell CN, Thorpe RJ. Early Life Racial Discrimination, Racial Centrality, and Allostatic Load Among African American Older Adults. Gerontologist. 2022 May 26;62(5):721-731. doi:10.1093/geront/gnab185. PMID: 34922345; PMCID: PMC9154246.
Thyagarajan B, Shippee N, Parsons H, Vivek S, Crimmins EM, Faul J, Shippee T. How Does Subjective Age Get “Under the Skin”? The Association Between Biomarkers and Feeling Older or Younger Than One’s Age: The Health and Retirement Study. Innov Aging. 2019;3(4):igz035. doi:10.1093/geroni/igz035. PMID: 31528718; PMCID: PMC6736363.
Tobin CST, Gutiérrez Á, Erving CL, Norris KC, Thorpe RJ Jr. When Resilience Becomes Risk: A Latent Class Analysis of Psychosocial Resources and Allostatic Load Among African American Men. Am J Mens Health. 2022 May-Jun;16(3):15579883221104272. doi:10.1177/15579883221104272. PMID: 35758236; PMCID: PMC9244943.
Seeman M, Merkin SS, Karlamangla A, Koretz B, Grzywacz JG, Lachman M, Seeman T. On the Biopsychosocial Costs of Alienated Labor. Work Employ Soc. 2021 Oct 1;35(5):891-913. doi:10.1177/0950017020952662. Epub 2021 Nov 17. PMID: 34707329; PMCID: PMC8547591.
Levine ME, Crimmins EM. Is 60 the New 50? Examining Changes in Biological Age Over the Past Two Decades. Demography. 2018 Apr;55(2):387-402. doi:10.1007/s13524-017-0644-5. PMID: 29511995; PMCID: PMC5897168.
Brown LL, Zhang YS, Mitchell C, Ailshire J. Does Telomere Length Indicate Biological, Physical, and Cognitive Health Among Older Adults? Evidence from the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2018 Nov 10;73(12):1626-1632. doi:10.1093/gerona/gly001. Erratum in: J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):905. doi:10.1093/gerona/gly088. PMID: 29346517; PMCID: PMC6230208.
Liu Z, Kuo PL, Horvath S, Crimmins E, Ferrucci L, Levine M. A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study. PLoS Med. 2018 Dec 31;15(12):e1002718. doi:10.1371/journal.pmed.1002718. Erratum in: PLoS Med. 2019 Feb 25;16(2):e1002760. doi:10.1371/journal.pmed.1002760. PMID: 30596641; PMCID: PMC6312200.
Meier HCS, Hussein M, Needham B, Barber S, Lin J, Seeman T, Diez Roux A. Cellular response to chronic psychosocial stress: Ten-year longitudinal changes in telomere length in the Multi-Ethnic Study of Atherosclerosis. Psychoneuroendocrinology. 2019 Sep;107:70-81. doi:10.1016/j.psyneuen.2019.04.018. Epub 2019 Apr 29. PMID: 31112903; PMCID: PMC6635040.
Rentscher KE, Carroll JE, Repetti RL, Cole SW, Reynolds BM, Robles TF. Chronic stress exposure and daily stress appraisals relate to biological aging marker p16(INK4a). Psychoneuroendocrinology. 2019 Apr;102:139-148. doi:10.1016/j.psyneuen.2018.12.006. Epub 2018 Dec 7. PMID: 30557761; PMCID: PMC6420375.
Brown L, García C, Ailshire J. Does Salivary Telomere Length Explain Race/Ethnic Differences in Aging? Biodemography Soc Biol. 2019 Oct-Dec;65(4):351-369. doi:10.1080/19485565.2020.1798736. Epub 2020 Nov 26. PMID: 33335644; PMCID: PMC7740300.
Upchurch DM, Rainisch BW, Chyu L. Greater Leisure Time Physical Activity Is Associated with Lower Allostatic Load in White, Black, and Mexican American Midlife Women: Findings from the National Health and Nutrition Examination Survey, 1999–2004. Womens Health Issues. 2015 Nov-Dec;25(6):680-687. doi:10.1016/j.whi.2015.07.002. Epub 2015 Sep 3. PMID: 26344446; PMCID: PMC4641768.
Friedman EM, Karlamangla AS, Gruenewald TL, Koretz B, Seeman TE. Early life adversity and adult biological risk profiles. Psychosom Med. 2015 Feb-Mar;77(2):176-185. doi:10.1097/PSY.0000000000000147. PMID: 25650548; PMCID: PMC4396808.
Brooks KP, Gruenewald T, Karlamangla A, Hu P, Koretz B, Seeman TE. Social relationships and allostatic load in the MIDUS study. Health Psychol. 2014 Nov;33(11):1373-1381. doi:10.1037/a0034528. Epub 2014 Jan 20. PMID: 24447186; PMCID: PMC4104264.
Levine ME, Crimmins EM. Evidence of accelerated aging among African Americans and its implications for mortality. Soc Sci Med. 2014 Oct;118:27-32. doi:10.1016/j.socscimed.2014.07.022. Epub 2014 Jul 15. PMID: 25086423; PMCID: PMC4197001.
Seeman M, Stein Merkin S, Karlamangla A, Koretz B, Seeman T. Social status and biological dysregulation: the “status syndrome” and allostatic load. Soc Sci Med. 2014 Oct;118:143-151. doi:10.1016/j.socscimed.2014.08.002. Epub 2014 Aug 5. PMID: 25112569; PMCID: PMC4167677.
Crimmins E, Ailshire J. Physical and Biological Indicators of Health and Functioning in U.S. Oldest Old. Annu Rev Gerontol Geriatr. 2013;33(1):193-215. doi:10.1891/0198-8794.33.193.
Goldman N, Turra CM, Rosero-Bixby L, Weir D, Crimmins E. Do biological measures mediate the relationship between education and health: A comparative study. Soc Sci Med. 2011 Jan;72(2):307-315. doi:10.1016/j.socscimed.2010.11.004. Epub 2010 Nov 23. PMID: 21159415; PMCID: PMC3039215.
Crimmins E, Vasunilashorn S, Kim JK, Alley D. Biomarkers related to aging in human populations. Adv Clin Chem. 2008;46:161-216. doi:10.1016/s0065-2423(08)00405-8. PMID: 19004190; PMCID: PMC5938178.
Dementia and Socioeconomic Status
Farina MP, Crimmins EM, Hayward MD. The role of southern context in shaping life course exposures linked to dementia incidence for Black and White older adults in the United States. BMC Geriatr. 2024 Nov 11;24(1):927. doi:10.1186/s12877-024-05508-x. PMID: 39528970; PMCID: PMC11552185.
Park S-Y, Setiawan VW, Crimmins EM, White LR, Wu AH, Cheng I, Haiman CA, Wilkens LR, Le Marchand L, Lim U. Racial and ethnic differences in the population-attributable fractions of Alzheimer disease and related dementias. Neurology. 2024;102(3). doi:10.1212/WNL.0000000000208116. Epub 2024 Jan 17. PMID: 38232335; PMCID: PMC11097758.
Ailshire JA, Walsemann KM, Fisk CE. Regional variation in U.S. dementia trends from 2000–2012. SSM Popul Health. 2022 Jul 7;19:101164. doi:10.1016/j.ssmph.2022.101164. PMID: 35855971; PMCID: PMC9287555.
Farina MP, Zhang YS, Kim JK, Hayward MD, Crimmins EM. Trends in dementia prevalence, incidence, and mortality in the United States (2000–2016). J Aging Health. 2022 Jan;34(1):100–108. doi:10.1177/08982643211029716. Epub 2021 Jul 7. PMID: 34233528; PMCID: PMC8989461.
Hayward MD, Farina MP, Zhang YS, Kim JK, Crimmins EM. The importance of improving educational attainment for dementia prevalence trends from 2000 to 2014 among older non-Hispanic Black and White Americans. J Gerontol B Psychol Sci Soc Sci. 2021 Oct 30;76(9):1870–1879. doi:10.1093/geronb/gbab015. PMID: 33481025; PMCID: PMC8557827.
Zhu Y, Chen Y, Crimmins EM, Zissimopoulos JM. Sex, race, and age differences in prevalence of dementia in Medicare claims and survey data. J Gerontol B Psychol Sci Soc Sci. 2021 Feb 17;76(3):596–606. doi:10.1093/geronb/gbaa083. PMID: 32588052; PMCID: PMC7887731.
Stokes AC, Weiss J, Lundberg DJ, Xie W, Kim JK, Preston SH, Crimmins EM. Estimates of the association of dementia with U.S. mortality levels using linked survey and mortality records. JAMA Neurol. 2020 Dec 1;77(12):1543–1550. doi:10.1001/jamaneurol.2020.2831. PMID: 32852519; PMCID: PMC7445631.
Farina MP, Hayward MD, Kim JK, Crimmins EM. Racial and educational disparities in dementia and dementia-free life expectancy. J Gerontol B Psychol Sci Soc Sci. 2020 Aug 13;75(7):e105–e112. doi:10.1093/geronb/gbz046. PMID: 31111926; PMCID: PMC7530490.
Saenz JL, Beam CR, Zelinski EM. The association between spousal education and cognitive ability among older Mexican adults. J Gerontol B Psychol Sci Soc Sci. 2020 Aug 13;75(7):e129–e140. doi:10.1093/geronb/gbaa002. PMID: 31974544; PMCID: PMC7424282.
Chen Y, Tysinger B, Crimmins E, Zissimopoulos JM. Analysis of dementia in the U.S. population using Medicare claims: insights from linked survey and administrative claims data. Alzheimers Dement (N Y). 2019 Jun 6;5:197–207. doi:10.1016/j.trci.2019.04.003. PMID: 31198838; PMCID: PMC6556828.
Metabolomics
Xu K, Hernández B, Arpawong TE, Camuzeaux S, Chekmeneva E, Crimmins EM, Elliott P, Fiorito G, Jiménez B, Kenny RA, McCrory C, McLoughlin S, Pinto R, Sands C, Vineis P, Lau CE, Robinson O. Assessing metabolic ageing via DNA methylation surrogate markers: a multicohort study in Britain, Ireland, and the USA. Aging Cell. 2025 May;24(5):e14484. doi:10.1111/acel.14484. Epub 2025 Jan 20. PMID: 39829316; PMCID: PMC12073893.
Cognitive Function and Aging
Nichols E, Lee J, Gross AL, Anwar M, Gupta A, Crimmins EM, Thyagarajan B, Dey S. Associations between blood-based neurodegenerative biomarkers and cognitive functioning and decline in India. J Alzheimers Dis. 2025 Sep;107(1):233–245. doi:10.1177/13872877251361934. Epub 2025 Jul 23. PMID: 40702821.
Kim JK, Anwar M, Gupta A, Thyagarajan B, Hu P, Faul JD, Weir DR, Langa KM, Lee J, Dey S, Crimmins EM. Association of blood-based neurodegenerative biomarkers with cognitive functioning and dementia in India (LASI-DAD) and the United States (HRS). Am J Epidemiol. 2025 Aug 21:kwaf179. doi:10.1093/aje/kwaf179. Epub ahead of print. PMID: 40838581; NIHMSID: 2114315.
Gross AL, Nichols E, Rentería MA, Khobragade PY, Meijer E, Ganguli M, Crimmins EM, Dey S, Dey AB, Lee J; LASI-DAD Authorship Team. Risk and protective factors against cognitive decline in older adults from a nationally representative sample in India: results from the LASI-DAD. medRxiv [Preprint]. 2025 Jul 10:2025.07.07.25331027. doi:10.1101/2025.07.07.25331027. PMID: 40672514; PMCID: PMC12265744.
Klopack ET, Farina MP, Thyagarajan B, Faul JD, Crimmins EM. How much can biomarkers explain sociodemographic inequalities in cognitive dysfunction and cognitive impairment? Results from a machine learning model in the Health and Retirement Study. J Alzheimers Dis. 2025 Jul;106(1):54–68. doi:10.1177/13872877251338063. Epub 2025 May 5. PMID: 40325957; PMCID: PMC12385895.
Forrester SN, Gallo JJ, Leoutsakos JM, Thorpe RJ Jr, Hughes TM, Fitzpatrick AL, Rapp SR, Seeman TE. Measuring the interrelationships between cognitive performance, race/ethnicity, discrimination, health behaviors, and physiological dysregulation: A path analysis of the Multi-Ethnic Study of Atherosclerosis. J Aging Health. 2025 Mar;37(3-4_suppl):40S-52S. doi: 10.1177/08982643241309457. Epub 2025 Mar 23. PMID: 40123184.
Imms P, Chaudhari NN, Chowdhury NF, Wang H, Yu X, Amgalan A, Irimia A. Neuroanatomical and clinical factors predicting future cognitive impairment. Geroscience. 2025 Feb;47(1):915–934. doi:10.1007/s11357-024-01310-0. Epub 2024 Aug 17. PMID: 39153054; PMCID: PMC11872856.
Walsemann KM, Jackson H, Abbruzzi E, Ailshire JA. State-level education quality and trajectories of cognitive function by race and educational attainment. Milbank Q. 2024 Jul 10. doi:10.1111/1468-0009.12709. Epub ahead of print. PMID: 38984387; PMCID: PMC11576583.
Wu Q, Ailshire JA, Kim JK, Crimmins EM. The association between cardiometabolic risk and cognitive function among older Americans and Chinese. J Gerontol A Biol Sci Med Sci. 2024 Jul 1;79(7):glae116. doi:10.1093/gerona/glae116. PMID: 38699992; PMCID: PMC11157968.
Walsemann KM, Hair NL, Farina MP, Tyagi P, Jackson H, Ailshire JA. State-level desegregation in the U.S. South and mid-life cognitive function among Black and White adults. Soc Sci Med. 2023 Dec;338:116319. doi:10.1016/j.socscimed.2023.116319. Epub 2023 Oct 15. PMID: 37871395; PMCID: PMC10872867.
Mawhorter SL, Wilkie RZ, Ailshire JA. Inequality in housing transitions during cognitive decline. PLoS One. 2023 Apr 12;18(4):e0282329. doi:10.1371/journal.pone.0282329. PMID: 37043418; PMCID: PMC10096249.
Walsemann KM, Ureña S, Farina MP, Ailshire JA. Race inequity in school attendance across the Jim Crow South and its implications for Black–White disparities in trajectories of cognitive function among older adults. J Gerontol B Psychol Sci Soc Sci. 2022 Aug 11;77(8):1467–1477. doi:10.1093/geronb/gbac026. PMID: 35139199; PMCID: PMC9371452.
Walsemann KM, Kerr EM, Ailshire JA, Herd P. Black–White variation in the relationship between early educational experiences and trajectories of cognitive function among U.S.-born older adults. SSM Popul Health. 2022 Jul 31;19:101184. doi:10.1016/j.ssmph.2022.101184. PMID: 35958228; PMCID: PMC9358471.
Henderson AK, Walsemann KM, Ailshire JA. Religious involvement and cognitive functioning at the intersection of race–ethnicity and gender among midlife and older adults. J Gerontol B Psychol Sci Soc Sci. 2022 Jan 12;77(1):237–248. doi:10.1093/geronb/gbab034. PMID: 33640966; PMCID: PMC8923294.
Marquez I, Garcia-Cifuentes E, Velandia FR, Iragorri A, Saavedra AM, Borda MG, Osuna M, Ailshire J, Cano-Gutierrez CA. Motoric cognitive risk syndrome: prevalence and cognitive performance. A cross-sectional study. Lancet Reg Health Am. 2022 Apr;8:100162. doi:10.1016/j.lana.2021.100162. eCollection 2022 Apr. PMID: 36778728; PMCID: PMC9904094.
Saenz JL, Díaz-Venegas C, Crimmins EM. Fertility history and cognitive function in late life: the case of Mexico. J Gerontol B Psychol Sci Soc Sci. 2021 Mar 14;76(4):e140–e152. doi:10.1093/geronb/gbz129. PMID: 31603514; PMCID: PMC7955970.
Walsemann KM, Ailshire JA. Early educational experiences and trajectories of cognitive functioning among U.S. adults in midlife and later. Am J Epidemiol. 2020 May 5;189(5):403–411. doi:10.1093/aje/kwz276. PMID: 31907547; PMCID: PMC7443204.
Levine ME, Harrati A, Crimmins EM. Predictors and implications of accelerated cognitive aging. Biodemography Soc Biol. 2018;64(2):83–101. doi:10.1080/19485565.2018.1552513. Epub 2018 Dec 20. PMID: 31007841; PMCID: PMC6469682.
Yen K, Wan J, Mehta HH, Miller B, Christensen A, Levine ME, Salomon MP, Brandhorst S, Xiao J, Kim SJ, Navarrete G, Campo D, Harry GJ, Longo V, Pike CJ, Mack WJ, Hodis HN, Crimmins EM, Cohen P. Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans. Sci Rep. 2018 Sep 21;8(1):14212. doi:10.1038/s41598-018-32616-7. PMID: 30242290; PMCID: PMC6154958.
Karlamangla AS, Miller-Martinez D, Lachman ME, Tun PA, Koretz BK, Seeman TE. Biological correlates of adult cognition: Midlife in the United States (MIDUS). Neurobiol Aging. 2014 Feb;35(2):387–394. doi:10.1016/j.neurobiolaging.2013.07.028. Epub 2013 Sep 5. PMID: 24011541; PMCID: PMC3830604.
Life Expectancy
Crimmins EM. Life expectancy and health expectancy in the twenty-first century: the unthinkable, the inconceivable, and the unknowable. Demography. 2025 Aug 1;62(4):1217–1236. doi:10.1215/00703370-12185960. PMID: 40771033; NIHMSID: 2114317.
Crimmins EM. Recent trends and increasing differences in life expectancy present opportunities for multidisciplinary research on aging. Nat Aging. 2021 Jan;1(1):12–13. doi:10.1038/s43587-020-00016-0. Epub 2021 Jan 14. PMID: 34355199; PMCID: PMC8336715.
Zhang YS, Saito Y, Crimmins EM. Changing impact of obesity on active life expectancy of older Americans. J Gerontol A Biol Sci Med Sci. 2019 Nov 13;74(12):1944–1951. doi:10.1093/gerona/glz133. PMID: 31120111; PMCID: PMC6853657.
Genomics, Genes and Gene Expression
Wu Q, Klopack ET, Kim JK, Arpawong TE, Thyagarajan B, Cole S, Faul JD, Zhou F, Crimmins EM. Gene expression composite scores of cellular senescence predict aging health outcomes in the Health and Retirement Study. Nat Commun. In press.
Arpawong TE, Gatz M, Zavala C, Gruenewald TL, Walters EE, Prescott CA. Nature, nurture, and the meaning of educational attainment: differences by sex and socioeconomic status. Twin Res Hum Genet. 2023 Feb;26(1):1–9. doi:10.1017/thg.2023.6. Epub 2023 Mar 13. PMID: 36912114; PMCID: PMC10497722.
Li MJ, Richter EI, Okafor CN, Kalmin MM, Dalvie S, Takada S, Gorbach PM, Shoptaw SJ, Cole SW. Social genomics of methamphetamine use, HIV viral load, and social adversity. Ann Behav Med. 2022 Aug 30;56(9):900–908. doi:10.1093/abm/kaab096. PMID: 36039526; PMCID: PMC9424866.
Li MJ, Takada S, Okafor CN, Gorbach PM, Shoptaw SJ, Cole SW. Experienced homophobia and gene expression alterations in Black and Latino men who have sex with men in Los Angeles County. Brain Behav Immun. 2020 Jan;83:120–125. doi:10.1016/j.bbi.2019.09.021. Epub 2019 Sep 26. PMID: 31563693; PMCID: PMC6906252.
Black DS, Christodoulou G, Cole S. Mindfulness meditation and gene expression: a hypothesis-generating framework. Curr Opin Psychol. 2019 Aug;28:302–306. doi:10.1016/j.copsyc.2019.06.004. Epub 2019 Jul 11. PMID: 31352296; PMCID: PMC6778024.
Liu Z, Chen X, Gill TM, Ma C, Crimmins EM, Levine ME. Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: evidence from the Health and Retirement Study. PLoS Med. 2019 Jun 18;16(6):e1002827. doi:10.1371/journal.pmed.1002827. PMID: 31211779; PMCID: PMC6581243.
Robinette JW, Boardman JD, Crimmins EM. Differential vulnerability to neighbourhood disorder: a gene × environment interaction study. J Epidemiol Community Health. 2019 May;73(5):388–392. doi:10.1136/jech-2018-211373. Epub 2019 Jan 19. PMID: 30661031; PMCID: PMC6935762.
Ross KM, Cole SW, Carroll JE, Dunkel Schetter C. Elevated pro-inflammatory gene expression in the third trimester of pregnancy in mothers who experienced stressful life events. Brain Behav Immun. 2019 Feb;76:97–103. doi:10.1016/j.bbi.2018.11.009. Epub 2018 Nov 14. PMID: 30447280; PMCID: PMC6348125.
Murray DR, Haselton MG, Fales M, Cole SW. Subjective social status and inflammatory gene expression. Health Psychol. 2019 Feb;38(2):182–186. doi:10.1037/hea0000705. PMID: 30652915; PMCID: PMC6592277.
Black DS, Cole SW, Christodoulou G, Figueiredo JC. Genomic mechanisms of fatigue in survivors of colorectal cancer. Cancer. 2018 Jun 15;124(12):2637–2644. doi:10.1002/cncr.31356. Epub 2018 Mar 26. PMID: 29579369; PMCID: PMC5990448.
Robinette JW, Boardman JD, Crimmins E. Perceived neighborhood social cohesion and cardiometabolic risk: a gene × environment study. Biodemography Soc Biol. 2018 Jul–Sep;64(3–4):173–186. doi:10.1080/19485565.2019.1579084. PMID: 31852333; PMCID: PMC6927540.
Levine ME, Crimmins EM, Weir DR, Cole SW. Contemporaneous social environment and the architecture of late-life gene expression profiles. Am J Epidemiol. 2017 Sep 1;186(5):503–509. doi:10.1093/aje/kwx147. PMID: 28911009; PMCID: PMC5860329.
Arpawong TE, Pendleton N, Mekli K, McArdle JJ, Gatz M, Armoskus C, Knowles JA, Prescott CA. Genetic variants specific to aging-related verbal memory: insights from GWASs in a population-based cohort. PLoS One. 2017 Aug 11;12(8):e0182448. doi:10.1371/journal.pone.0182448. PMID: 28800603; PMCID: PMC5553750.
Carroll JE, Irwin MR, Levine M, Seeman TE, Absher D, Assimes T, Horvath S. Epigenetic aging and immune senescence in women with insomnia symptoms: findings from the Women’s Health Initiative Study. Biol Psychiatry. 2017 Jan 15;81(2):136–144. doi:10.1016/j.biopsych.2016.07.008. Epub 2016 Jul 26. PMID: 27702440; PMCID: PMC5536960.
Levine ME, Crimmins EM, Prescott CA, Phillips D, Arpawong TE, Lee J. A polygenic risk score associated with measures of depressive symptoms among older adults. Biodemography Soc Biol. 2014;60(2):199–211. doi:10.1080/19485565.2014.952705. PMID: 25343367; PMCID: PMC4298361.
Levine ME, Cole SW, Weir DR, Crimmins EM. Childhood and later life stressors and increased inflammatory gene expression at older ages. Soc Sci Med. 2015 Apr;130:16–22. doi:10.1016/j.socscimed.2015.01.030. Epub 2015 Jan 21. PMID: 25658624; PMCID: PMC4394113.
Vedhara K, Gill S, Eldesouky L, Campbell BK, Arevalo JM, Ma J, Cole SW. Personality and gene expression: do individual differences exist in the leukocyte transcriptome? Psychoneuroendocrinology. 2015 Feb;52:72–82. doi:10.1016/j.psyneuen.2014.10.028. Epub 2014 Nov 11. PMID: 25459894; PMCID: PMC4297539.
Knight JM, Rizzo JD, Logan BR, Wang T, Arevalo JM, Ma J, Cole SW. Low socioeconomic status, adverse gene expression profiles, and clinical outcomes in hematopoietic stem cell transplant recipients. Clin Cancer Res. 2016 Jan 1;22(1):69–78. doi:10.1158/1078-0432.CCR-15-1344. Epub 2015 Aug 18. PMID: 26286914; PMCID: PMC4703514.
Carroll JE, Cole SW, Seeman TE, Breen EC, Witarama T, Arevalo JMG, Ma J, Irwin MR. Partial sleep deprivation activates the DNA damage response (DDR) and the senescence-associated secretory phenotype (SASP) in aged adult humans. Brain Behav Immun. 2016 Jan;51:223–229. doi:10.1016/j.bbi.2015.08.024. Epub 2015 Aug 31. PMID: 26336034; PMCID: PMC4679552.
Levine ME, Crimmins EM. A genetic network associated with stress resistance, longevity, and cancer in humans. J Gerontol A Biol Sci Med Sci. 2016 Jun;71(6):703–712. doi:10.1093/gerona/glv141. Epub 2015 Sep 9. PMID: 26355015; PMCID: PMC4888382.
McDade TW, Ross KM, Fried RL, Arevalo JM, Ma J, Miller GE, Cole SW. Genome-wide profiling of RNA from dried blood spots: convergence with bioinformatic results derived from whole venous blood and peripheral blood mononuclear cells. Biodemography Soc Biol. 2016;62(2):182–197. doi:10.1080/19485565.2016.1185600. PMID: 27337553; PMCID: PMC4972449.
Arpawong TE, Lee J, Phillips DF, Crimmins EM, Levine ME, Prescott CA. Effects of recent stress and variation in the serotonin transporter polymorphism (5-HTTLPR) on depressive symptoms: a repeated-measures study of adults age 50 and older. Behav Genet. 2016 Jan;46(1):72–88. doi:10.1007/s10519-015-9740-8. Epub 2015 Sep 2. PMID: 26330209; PMCID: PMC4720538.
Vasunilashorn S, Finch CE, Crimmins EM, Vikman SA, Stieglitz J, Gurven M, Kaplan H, Allayee H. Inflammatory gene variants in the Tsimane, an indigenous Bolivian population with a high infectious load. Biodemography Soc Biol. 2011;57(1):33–52. doi:10.1080/19485565.2011.564475. PMID: 21845926; PMCID: PMC3529658.
Immune Function
Bather JR, Kranz EO, Rodrigues M, Cole SW, Cuevas AG. Discrimination and dendritic cell abundance among older adults in the health and retirement study. Brain Behav Immun. 2025 Aug 22;130:106087. doi:10.1016/j.bbi.2025.106087. PMID: 40850376.
Klopack E. Chronic stress and latent virus reactivation: Effects on immune aging, chronic disease morbidity, and mortality. J Gerontol B Psychol Sci Soc Sci. 2023;78(10):1707-1716. doi:10.1093/geronb/gbad087. PMID: 37294880; PMCID: PMC10561893.
Seshadri G, Vivek S, Prizment A, Crimmins EM, Klopack E, Faul J, Guan W, Meier H, Thyagarajan B. Immune cells are associated with mortality: The Health and Retirement Study. Front Immunol. 2023;14:1280144. doi:10.3389/fimmu.2023.1280144. PMID: 37928548; PMCID: PMC10623116.
Ramasubramanian R, Kim JW, Guan W, Meier HCS, Crimmins EM, Faul J, Thyagarajan B. Cohabitation as a determinant of adaptive and innate immune cell profiles: Findings from the Health and Retirement Study. Brain Behav Immun Health. 2023;33:100676. doi:10.1016/j.bbih.2023.100676. PMID: 37663036; PMCID: PMC10474123.
Vivek S, Crimmins EM, Prizment AE, Meier HCS, Ramasubramanian R, Barcelo H, Faul J, Thyagarajan B. Age-related differences in T cell subsets and markers of subclinical inflammation in aging are independently associated with type 2 diabetes in the Health and Retirement Study. Can J Diabetes. 2023;S1499-2671(23)00136-3. doi:10.1016/j.jcjd.2023.05.010. Epub ahead of print. PMID: 37269981; PMCID: PMC10592537.
Klopack ET, Crimmins EM, Cole SW, Seeman TE, Carroll JE. Social stressors associated with higher percentage of age-related T lymphocytes in older US adults: Evidence from the Health and Retirement Study. Proc Natl Acad Sci U S A. 2022;119(25):e2202780119. doi:10.1073/pnas.2202780119. PMID: 35696572; PMCID: PMC9231620.
Ramasubramanian R, Meier HCS, Vivek S, Klopack ET, Crimmins EM, Faul J, Nikolich-Žugich J, Thyagarajan B. Evaluation of T-cell aging-related immune phenotypes in the context of biological aging and multimorbidity in the Health and Retirement Study. Immun Ageing. 2022;19(1):33. doi:10.1186/s12979-022-00290-z. PMID: 35858901; PMCID: PMC9297609.
Farina MP, Kim JK, Hayward MD, Crimmins EM. Links between inflammation and immune functioning with cognitive status among older Americans in the Health and Retirement Study. Brain Behav Immun Health. 2022;26:100559. doi:10.1016/j.bbih.2022.100559. PMID: 36439057; PMCID: PMC9694056.
Klopack ET, Thyagarajan B, Faul JD, Meier HCS, Ramasubramanian R, Kim JK, Crimmins EM. Socioeconomic status and age-related immunity in older US adults in the Health and Retirement Study. Biodemography Soc Biol. 2022;67(3–4):187-202. doi:10.1080/19485565.2022.2149465. PMID: 36472376; PMCID: PMC9869898.
Vivek S, Nelson HH, Prizment AE, Faul J, Crimmins EM, Thyagarajan B. Cross-sectional association between cytomegalovirus seropositivity, inflammation and cognitive impairment in elderly cancer survivors. Cancer Causes Control. 2021;32(12):1407-1419. doi:10.1007/s10552-021-01504-3. PMID: 34637066; PMCID: PMC8840815.
Thyagarajan B, Faul J, Vivek S, Kim JK, Nikolich-Žugich J, Weir D, Crimmins EM. Age-related differences in T-cell subsets in a nationally representative sample of people older than age 55: Findings from the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2022;77(5):927-933. doi:10.1093/gerona/glab300. Epub 2021 Oct 13. PMID: 34633448; PMCID: PMC9071411.
Cobb RJ, Parker LJ, Thorpe RJ. Self-reported instances of major discrimination, race/ethnicity, and inflammation among older adults: Evidence from the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2020 Jan 20;75(2):291-296. doi:10.1093/gerona/gly267. PMID: 30508069; PMCID: PMC8127073.
Donoho CJ, Crimmins EM, Seeman TE. Marital quality, gender, and markers of inflammation in the MIDUS cohort. J Marriage Fam. 2013;75(1):127-141. doi:10.1111/j.1741-3737.2012.01023.x. PMID: 24700968; PMCID: PMC3971932.
Other Papers
Choi JS, Adams ME, Crimmins EM, Lin FR, Ailshire J. Association between hearing aid use and mortality in US adults with hearing loss: a cross-sectional cohort mortality follow-up study. Lancet Healthy Longev. 2024;5(1). doi:10.1016/S2666-7568(23)00232-5. PMCID: PMC11501007.
Kang H, Kim JK, Ailshire J, Crimmins EM. Shingles vaccine uptake among older adults: identifying early, later, and non-adopters. AJPM Focus. 2023;2(4):100143. doi:10.1016/j.focus.2023.100143. eCollection 2023 Dec. PMID: 37920403; PMCID: PMC10618697.
Kemp BR, Ferraro KF, Morton PM, Thomas PA, Mustillo SA, Crimmins EM. Do early-life social and health exposures increase later-life arthritis incidence? Res Aging. 2021;43(10):810–828. doi:10.1177/01640275211044979. PMID: not listed; PMCID: PMC9016101.
Burgard S, Montez JK, Ailshire J, Hummer RA. Aging policy from a multilayered geographic and life course perspective. Public Policy Aging Rep. 2020 Dec 18;31(1):3–6. doi:10.1093/ppar/praa037. PMID: 33462549; PMCID: PMC7799384.
Frochen S, Rodnyansky S, Ailshire J. Residential care in California. J Maps. 2020;16(1):138–143. doi:10.1080/17445647.2020.1768446. Epub 2020 Jun 5. PMID: 33093858; PMCID: PMC7577399.
García C, Sheehan CM, Flores-Gonzalez N, Ailshire JA. Sleep patterns among US Latinos by nativity and country of origin: results from the National Health Interview Survey. Ethn Dis. 2020 Jan 16;30(1):119–128. doi:10.18865/ed.30.1.119. PMID: 31969791; PMCID: PMC6970521.
Sheehan CM, Frochen SE, Walsemann KM, Ailshire JA. Are U.S. adults reporting less sleep? Findings from sleep duration trends in the National Health Interview Survey, 2004–2017. Sleep. 2019 Feb 1;42(2):zsy221. doi:10.1093/sleep/zsy221. PMID: 30452725; PMCID: PMC6941709.
Crandall CJ, Karlamangla AS, Merkin SS, Binkley N, Carr D, Greendale GA, Seeman TE. Adult bone strength of children from single-parent families: the Midlife in the United States Study. Osteoporos Int. 2015 Mar;26(3):931–942. doi:10.1007/s00198-014-2990-0. Epub 2014 Dec 16. PMID: 25510582; PMCID: PMC4344315.
Miller-Martinez D, Seeman T, Karlamangla AS, Greendale GA, Binkley N, Crandall CJ. Marital histories, marital support, and bone density: findings from the Midlife in the United States Study. Osteoporos Int. 2014 Apr;25(4):1327–1335. doi:10.1007/s00198-013-2602-4. Epub 2014 Jan 15. Erratum in: Osteoporos Int. 2014 Apr;25(4):1425–1426. doi:10.1007/s00198-014-2630-8. PMID: 24424630; PMCID: PMC4027961.