The Biomarker Network

a National Institute of Aging sponsored project dedicated to improved measurement of biological risk for late-life health outcomes in large representative samples of populations.

 
 

Virtual NIA-Sponsored 2020 Biomarker Network Meeting

Because our annual PAA Biomarker Network in-person meeting was canceled due to the global COVID-19 pandemic, we organized a series of virtual sessions on June 19, 22, and 25 to present some of the material scheduled for the in-person meeting.

Virtual NIA-Sponsored 2020 Biomarker Network meeting

Because our annual PAA Biomarker Network in-person meeting was canceled due to the global COVID-19 pandemic, we organized a series of virtual sessions on June 19, 22, and 25 to present some of the material scheduled for the in-person meeting.

Virtual Biomarker Network Meeting – Biomarkers and Stress – Day 1 (June 16, 2020)

  • Moderator – Eileen Crimmins
How do war and stress contribute to subjective age? An analysis of biological, psychosocial and life course stress factors in the Vietnam Health and Aging Study
  • Kim Korinek, Eleanor Brindle, Jefferson Schmidt, Tran Khanh Toan, Zachary Zimmer
Cortisol concentrations in hair are reduced 14 years after exposure to a major natural disaster
  • Ralph Lawton, Elizabeth Frankenberg, Teresa Seeman, Eileen Crimmins, Cecep Sumantri, Duncan Thomas
Effect of violence crime in adolescent’s activity space on perceived and biological stress
  • Jodi L. Ford, Christopher R. Browning, Kammi Schmeer, Catherine Calder, Beth Boettner, & Jacob Tarrence
The role of early life environments in U.S. socioeconomic disparities in adult chronic inflammation
  • Stephanie Koning, Thomas McDade

Virtual Biomarker Network Meeting – Biomarkers and Health Outcomes – Day 2 (June 19, 2020)

  • Moderator – Teresa Seeman
Lifespan adversity and epigenetic age acceleration in the Irish Longitudinal Study on Ageing (TILDA)
  • Cathal McCrory, Giovanni Fiorito, Paolo Vineis, Rose Anne Kenny
Associations between changes in vitamin D levels and health in later life: evidence from the English longitudinal study of ageing
  • Giorgio Di Gessa, Paola Zaninotto, Cesar Messias de Oliveira Giorgio Di Gessa, Paola Zaninotto, Cesar Messias de Oliveira
The Interaction of age and mild cognitive impairment on brain morphometry: Neuroimaging analysis from the Longitudinal Aging Study in India: Diagnostic Assessment of Dementia (LASI-DAD)
  • Brenton Keller, Jorge Jovicich, Arthur Toga, Jinkook Lee
Biomeasures in the time of COVID19: remote self-administered collection
  • Martha K. McClintock, Joscelyn Hoffmann, Hannah You, Elbert Huang, Megan Huisingh-Scheetz, Jay Pinto, L. Phillip Schumm and Kristen Wroblewski

Virtual Biomarker Network Meeting – Telomere Measurement and Results – Day 3 (June 22, 2020)

  • Moderator – Steve Cole
Telomere Research Network
  • Stacy Drury
Telomere length estimates, lab to lab comparisons, and sample handling effects: Progress reports from multiple labs
  • Jude Carroll, Daniel Notterman Colter Mitchell, Jessica Faul
Demographic and developmental patterns in telomere length across adolescence
  • Lauren Gaydosh, Colter Mitchell, Daniel Notterman, Lisa Schneper, Jeanne Brooks-Gunn, Brandon Wagner, Kalsea Koss, and Sara McLanahan

The Biomarker Network is a National Institute of Aging sponsored project to develop an interdisciplinary group of scientists dedicated to improved measurement of biological risk for late life health outcomes in large representative samples of populations. Activities of the network include designing and carrying out a series of focused meetings, interactive activities, workshops, and pilot projects to harmonize and develop measurement of biological risk in populations.

Biological risk represents objective measurement of major dimensions of population health.  The level of risk can indicate the health of the population, need for health care treatment in a population, and the effectiveness of that treatment in controlling risk or delaying disease progression, and death.  The measurement of biological risk in large populations often requires adoption of methods not used in laboratory settings.  This project will improve the methods of measuring health used in populations and improve comparability of results over time and across studies, which is important for monitoring population health.

The Biomarker Network is funded through the National Institute on Aging (NIA) grant R24AG037898.

Aims of the Network

The overarching goal of the network is to promote interdisciplinary research that clarifies the biological paths to health outcomes that can be measured or monitored in population surveys.  The network will address the following questions:

  • What array of biological markers can be included reliably and validly in population studies in order to better monitor health and predict health outcomes at the older ages?

  • What are the best methods of collecting biological risk information under a variety of circumstances?

  • What are the best methods for processing the biological risk information collected?

  • What methods of harmonization will allow us to compare biological risk across studies?

  • What are the best approaches to measurement of cumulative biological risk or dimensions of biological risk for a variety of health outcomes in a variety of settings?

  • What are the best approaches in including indicators of genetic risk for complex diseases and conditions into data from population-based surveys?

  • How do we best capture indicators of life-long social, psychological and economic conditions along with lifelong biological risk to explain later life health outcomes?

  • What particular ethical issues are posed by our linking of biological data to extensive social, psychological, and economic information?

Contact Us

Eileen M. Crimmins

Director

USC Leonard Davis School of Gerontology
University of Southern California

Teresa E. Seeman

Director

David Geffen School of Medicine
University of California at Los Angeles

Heather McCreath

Director of Clinical Operations

Division of Geriatrics
David Geffen School of Medicine
University of California at Los Angeles

Lisbeth Nielsen

NIA Program Officer

National Institute of Aging
Division of Behavioral and Social Research