{"id":2066,"date":"2025-04-16T15:58:05","date_gmt":"2025-04-16T22:58:05","guid":{"rendered":"https:\/\/gero.usc.edu\/cbph\/?page_id=2066"},"modified":"2026-05-04T16:26:06","modified_gmt":"2026-05-04T23:26:06","slug":"biomarker-resources","status":"publish","type":"page","link":"https:\/\/gero.usc.edu\/cbph\/biomarker-resources\/","title":{"rendered":"Biomarker Resources"},"content":{"rendered":"[vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” row_position_desktop=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column 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desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][image_with_animation image_url=”2536″ image_size=”full” max_width=”100%” max_width_mobile=”default” animation_type=”entrance” animation=”None” animation_movement_type=”transform_y” hover_animation=”none” alignment=”” img_link_target=”lightbox” border_radius=”none” box_shadow=”none” image_loading=”default” screen_reader_text=”Link to Improving Study – Lab Collaborations document” 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Improving Study – Lab Collaborations<\/h3>\n

A practical framework for designing stronger biomarker studies<\/h4>\n

This diagram maps best practices across the full biospecimen-to-data pipeline, helping teams reduce friction, standardize processes, and generate high-quality, reliable data through early planning, quality control, and clear communication.[\/vc_column_text][nectar_cta btn_style=”basic” heading_tag=”span” link_type=”regular” button_color=”accent-color” text_color=”#FFFFFF” button_border_thickness=”0px” alignment=”left” alignment_tablet=”default” alignment_phone=”default” constrain_group_3=”yes” constrain_group_4=”yes” display=”block” display_tablet=”inherit” display_phone=”inherit” icon_family=”iconsmind” link_text=”Download Improving Study – Lab Collaborations” url=”https:\/\/gero.usc.edu\/cbph\/wp-content\/uploads\/2026\/04\/ImprovingBiomarkerStudy-LabCollaborations-2.pdf” aria_label_text=”Download Improving Study – Lab Collaborations” icon_iconsmind=”iconsmind-Download2″ padding_top=”20px” padding_bottom=”20px” padding_left=”20px” padding_right=”20px”][divider line_type=”Full Width Line” line_thickness=”1″ divider_color=”default” custom_height=”100″ custom_height_tablet=”100″ custom_height_phone=”50″][vc_column_text css=”” text_direction=”default”]\n

Standard Operating Procedure<\/h3>\n

Biospecimen Collection & Lab Partnership Management<\/h4>\n

As biomarker collection becomes increasingly central to population health and aging research, the success of studies depends on strong, well-coordinated collaborations between study teams and laboratories. This SOP provides standardized guidance for population study teams planning and executing biospecimen collection and managing lab partnerships.<\/p>\n

Who this is for:<\/strong> Study PIs, data managers, field coordinators, and program staff working on population-based longitudinal studies, cohort surveys, and multi-site research that involves biospecimen collection and laboratory analysis.[\/vc_column_text][nectar_cta btn_style=”basic” heading_tag=”span” link_type=”regular” button_color=”accent-color” text_color=”#FFFFFF” button_border_thickness=”0px” alignment=”left” alignment_tablet=”default” alignment_phone=”default” constrain_group_3=”yes” constrain_group_4=”yes” display=”block” display_tablet=”inherit” display_phone=”inherit” icon_family=”iconsmind” link_text=”Download Standard Operating Procedure” url=”https:\/\/gero.usc.edu\/cbph\/wp-content\/uploads\/2026\/04\/SOP_Study_Teams.pdf” aria_label_text=”Download Standard Operating Procedure document” icon_iconsmind=”iconsmind-Download2″ padding_top=”20px” padding_bottom=”20px” padding_left=”20px” padding_right=”20px”][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” top_padding=”3%” constrain_group_1=”yes” bottom_padding=”3%” top_padding_tablet=”5%” constrain_group_3=”yes” bottom_padding_tablet=”5%” top_padding_phone=”10%” constrain_group_5=”yes” bottom_padding_phone=”10%” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” row_position_desktop=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” id=”biomarker-collection-protocols” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” 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tab_color=”Accent-Color” vs_content_animation=”fade” vs_link_animation=”opacity” vs_navigation_alignment=”left” vs_navigation_width_2=”25%” vs_navigation_func=”default” vs_navigation_width=”regular” vs_navigation_spacing=”15px” vs_navigation_mobile_display=”visible” vs_tab_spacing=”5%”][tab icon_family=”none” title=”Hair Collection Protocol” id=”1777936989906-3″ tab_id=”1777936989908-6″][vc_custom_heading text=”Hair Collection Protocol” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes” css=””][vc_row_inner column_margin=”30px” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_video link=”https:\/\/youtu.be\/NfjlqJtmlSQ” css=””][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text css=”.vc_custom_1743199940539{border-radius: 1px !important;}” text_direction=”default”]Cortisol and other stress-related steroids can be measured in hair, providing a long-term indicator of hormone levels over weeks to months. This method differs from traditional blood and saliva tests, which capture short-term fluctuations. While hair analysis offers unique insights into chronic stress, research is still ongoing to fully understand how these measurements compare to those from blood and saliva, as factors like hair growth and external influences may affect results.[\/vc_column_text][nectar_btn size=”large” open_new_tab=”true” button_style=”regular” button_color_2=”Accent-Color” icon_family=”none” text=”Hair Collection Protocol” url=”https:\/\/gero.usc.edu\/cbph\/wp-content\/uploads\/2025\/04\/Hair-Collection-Protocol.pdf”][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Dried Blood Spot Collection” id=”1777936989991-0″ tab_id=”1777936989992-8″][vc_custom_heading text=”Dried Blood Spot Collection” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes” css=””][vc_row_inner column_margin=”30px” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_video link=”https:\/\/youtu.be\/exOg6Y-FE30″ align=”center” css=””][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text css=”” text_direction=”default”]Dried blood spot (DBS) collection is a minimally invasive, cost-effective method for obtaining blood samples for biomarker testing. It enables large-scale, population-based research by allowing easy collection, storage, and transport of biological samples, even in remote or resource-limited settings.[\/vc_column_text][nectar_btn size=”large” open_new_tab=”true” button_style=”regular” button_color_2=”Accent-Color” icon_family=”none” text=”Dried Blood Spot Collection Protocol” url=”https:\/\/gero.usc.edu\/cbph\/wp-content\/uploads\/2025\/04\/Dried-Blood-Spot-Collection.pdf” aria_label_text=”Link to Dried Blood Spot Collection resource”][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Saliva Collection using Salivettes” id=”1777936990051-3″ tab_id=”1777936990052-8″][vc_custom_heading text=”Saliva Collection using Salivettes” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes” css=””][vc_row_inner column_margin=”30px” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_video link=”https:\/\/youtu.be\/3bc3SSCNfXc?feature=shared” css=””][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text css=”” text_direction=”default”]Saliva collection using Salivettes offers a standardized, non-invasive method for biomarker assessment in population-based studies. This approach enables reliable measurement of key analytes\u2014such as cortisol, DHEA, and inflammatory markers\u2014while facilitating easy collection, storage, and transport across diverse research settings. Salivettes are particularly valuable for studies requiring repeated measures or field-based biospecimen collection.[\/vc_column_text][nectar_btn size=”large” open_new_tab=”true” button_style=”regular” button_color_2=”Accent-Color” icon_family=”none” text=”Proper Use of Salivettes Protocol” url=”https:\/\/gero.usc.edu\/cbph\/wp-content\/uploads\/2025\/04\/Saliva-Collection-using-Salivettes.pdf” aria_label_text=”Link to Saliva Collection Protocol Resource”][\/vc_column_inner][\/vc_row_inner][\/tab][tab icon_family=”none” title=”Processing CPT Tubes” id=”1777936990103-2″ tab_id=”1777936990103-8″][vc_custom_heading text=”Processing CPT Tubes” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes” css=””][vc_row_inner column_margin=”30px” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_video link=”https:\/\/youtu.be\/ldoj6plKhNw” css=””][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” overflow=”visible” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text css=”” text_direction=”default”]Peripheral Blood Mononuclear Cells (PBMCs)<\/strong> are essential for immunological research, including studies of immune function, inflammation, and disease pathogenesis. Cell Preparation Tubes (CPTs)<\/strong> offer an efficient, standardized method for PBMC isolation directly from whole blood. 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