Portrait of Hongqiao Zhang

Hongqiao Zhang, MD, PhD

Research Assistant Professor of Gerontology

Expertise: Environment, Alzheimer's and dementia, Stress response


  • Postdoctoral Training, University of California, Merced, 2008
  • PhD, University of Alabama at Birmingham, 2005
  • MPH, Chinese Center for Disease Control and Prevention, China, 1996
  • MD, Shandong University, China, 1993


Hongqiao Zhang, MD, PhD, researches the regulation of antioxidant and detoxifying genes in response to oxidative stress. Nrf2 is a transcription factor that regulates the basal and adaptive induction of a series of antioxidant and detoxifying genes. Nrf2 activity declines with aging and subsequently leads to decreased induction of antioxidant genes and impaired adaptive response to oxidative stress in the elderly. The Zhang lab is particularly interested in elucidating the underlying mechanism of how Nrf2 signaling declines with aging and its involvement in age-related diseases. Currently, his lab works on two projects, one is to investigate the effect of aging on the activation of Nrf2 signaling in response to ambient nanoparticle exposure, and another is to study the different inflammatory response of young and old to ambient nanoparticles. The final goal is to provide insight into how older adults may be more susceptible to air pollution and other environmental toxicants.

Email: hongqiaz@usc.edu

Office Location: GER 313D

Office Phone: (626) 272-7968

Publications and links:

Curriculum Vitae