{"id":1446,"date":"2025-01-22T16:33:22","date_gmt":"2025-01-23T00:33:22","guid":{"rendered":"https:\/\/gero.usc.edu\/laara\/?page_id=1446"},"modified":"2026-01-30T15:05:45","modified_gmt":"2026-01-30T23:05:45","slug":"clinical-trials","status":"publish","type":"page","link":"https:\/\/gero.usc.edu\/laara\/clinical-trials\/","title":{"rendered":"Clinical Trials"},"content":{"rendered":"[vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” top_padding=”3%” constrain_group_1=”yes” bottom_padding=”3%” top_padding_tablet=”5%” constrain_group_3=”yes” bottom_padding_tablet=”5%” top_padding_phone=”10%” constrain_group_5=”yes” bottom_padding_phone=”10%” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text css=”” text_direction=”default”]\n

A Nutritional Intervention for Body, Brain, and Longevity Effects (NIBBLE)<\/span><\/b><\/a>\u00a0<\/span><\/h3>\n

The study aims to evaluate the safety, feasibility, and efficacy of six-month fasting-mimicking (FMD) intervention in middle-aged adults at elevated risk for Alzheimer’s disease due to the apolipoprotein (APOE) \u03b54 allele.<\/span>\u00a0<\/span><\/p>\n

\n

Endoscopic Intestinal Re-Cellularization Therapy in Type II Diabetes (ReCET Study)<\/strong><\/a><\/h3>\n<\/div>\n

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the ReCET Intestinal Cellular Regeneration System for improving glycemic (blood sugar) control in individuals with type 2 diabetes.<\/p>\n

Pragmatic Evaluation of events And Benefits of Lipid-lowering in older adults (PREVENTABLE)<\/span><\/b><\/a>\u00a0<\/span><\/h3>\n

The purpose of this multi-site study is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability or heart disease.\u00a0<\/span>\u00a0<\/span><\/p>\n

Single Nuclei RNA-Seq to MAP Adipose Cellular Populations and Senescent Cells in Older Subjects<\/span><\/b><\/a>\u00a0<\/span><\/h3>\n

The purpose of this study is to evaluate whether senescent cells (cells that age and permanently stop dividing but do not die) affect the body\u2019s ability to metabolize (process sugars).\u00a0<\/span>\u00a0<\/span><\/p>\n

The KAAP-Sen Tissue Mapping Center (TMC) Collaborative<\/a><\/strong><\/h3>\n

The purpose of this study is to understand the role of senescent cells. A senescent cell is a cell that ages and permanently stops dividing but does not die. Researchers want to learn how these cells work in fat tissue in relation to the aging process.<\/p>\n

Molecular Transducers of Physical Activity Consortium<\/span><\/b><\/a> (Recruitment Closed)<\/span><\/h3>\n

The purpose of this study is to understand how exercise affects the cells and tissues in the body to bring about health benefits.<\/span>\u00a0<\/span><\/p>\n

Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of Alzheimer\u2019s Disease<\/span><\/b><\/a> (Recruitment Closed)<\/span><\/h3>\n

The purpose of this study is to determine whether a medication called emtricitabine is safe and tolerable in people with mild to moderate Alzheimer\u2019s disease (AD).<\/span>\u00a0<\/span><\/p>\n

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