{"id":6,"date":"2017-09-25T22:06:14","date_gmt":"2017-09-25T22:06:14","guid":{"rendered":"http:\/\/gerousc.com\/labs\/cohenlab\/?page_id=6"},"modified":"2025-06-10T21:55:34","modified_gmt":"2025-06-10T21:55:34","slug":"publications","status":"publish","type":"page","link":"https:\/\/gero.usc.edu\/labs\/cohenlab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

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  1. Shemtov, SJ, McGann, E, Carrillo, L, Lee, S, Anson, H, Hwang, E et al.<\/i>. The longevity effects of reduced IGF-1 signaling depend on the stability of the mitochondrial genome. Sci Adv. 2026;12 (14):eaea4279. doi: 10.1126\/sciadv.aea4279<\/a>. PubMed PMID:41931604<\/a> PubMed Central PMC13048258<\/a>.<\/li>
  2. Vicinanza, R, Cammisotto, V, Wan, J, Yen, K, Violi, F, Pignatelli, P et al.<\/i>. Mediterranean diet adherence is associated with mitochondrial microproteins Humanin and SHMOOSE; potential role of the Humanin-Nox2 interaction in cardioprotection. Front Nutr. 2025;12 :1727012. doi: 10.3389\/fnut.2025.1727012<\/a>. PubMed PMID:41883858<\/a> PubMed Central PMC13008867<\/a>.<\/li>
  3. Behan, M, Yen, K, Cohen, P, Kliment, CR. Mitochondrial-derived microproteins in lung disease: insights and implications. Am J Physiol Lung Cell Mol Physiol. 2026;330 (3):L222-L231. doi: 10.1152\/ajplung.00369.2025<\/a>. PubMed PMID:41569667<\/a> PubMed Central PMC12961588<\/a>.<\/li>
  4. Yoon, SH, Yuan, F, Zhu, X, Tang, H, Abdurakhimoova, D, Krier, J et al.<\/i>. Systemic MOTS-c levels are increased in adults with obesity in association with metabolic dysregulation and remain unchanged after weight loss. J Clin Transl Endocrinol. 2026;43 :100429. doi: 10.1016\/j.jcte.2025.100429<\/a>. PubMed PMID:41551324<\/a> PubMed Central PMC12807633<\/a>.<\/li>
  5. Omidsalar, AA, Tyrpak, DR, MacKay, JA, Yen, K, Cohen, P, Serrano, G et al.<\/i>. Mitochondrial DNA Variation in the Aging Human Cerebral Cortex and Cerebellum. Aging Cell. 2026;25 (1):e70340. doi: 10.1111\/acel.70340<\/a>. PubMed PMID:41432549<\/a> PubMed Central PMC12724393<\/a>.<\/li>
  6. Soni, S, Mittal, P, Lo, JH, Yang, Y, Smbatyan, G, Lee, K et al.<\/i>. Age-diet interactions significantly influence intratumoral gene expression, gut microbiome signature and tumor microenvironment in colorectal cancer. Neoplasia. 2025;70 :101245. doi: 10.1016\/j.neo.2025.101245<\/a>. PubMed PMID:41201920<\/a> PubMed Central PMC12596543<\/a>.<\/li>
  7. Shemtov, SJ, McGann, E, Carrillo, L, Lee, S, Anson, H, Chung, CS et al.<\/i>. The longevity effects of reduced IGF-1 signaling depend on the stability of the mitochondrial genome. bioRxiv. 2025; :. doi: 10.1101\/2025.06.03.656903<\/a>. PubMed PMID:40501628<\/a> PubMed Central PMC12157428<\/a>.<\/li>
  8. Flores, MK, Janes, JL, Islam, M, Wan, J, Liu, J, Reams, RR et al.<\/i>. Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals. Cancer Prev Res (Phila). 2025;18 (9):541-550. doi: 10.1158\/1940-6207.CAPR-24-0401<\/a>. PubMed PMID:40358482<\/a> PubMed Central PMC12354066<\/a>.<\/li>
  9. Yen, K, Miller, B, Kumagai, H, Silverstein, A, Cohen, P. Mitochondrial-derived microproteins: from discovery to function: (Trends in Genetics, 41:2 pp:132-145, 2025). Trends Genet. 2025;41 (4):357. doi: 10.1016\/j.tig.2025.02.003<\/a>. PubMed PMID:40050129<\/a> .<\/li>
  10. Yen, K, Miller, B, Kumagai, H, Silverstein, A, Cohen, P. Mitochondrial-derived microproteins: from discovery to function. Trends Genet. 2025;41 (2):132-145. doi: 10.1016\/j.tig.2024.11.010<\/a>. PubMed PMID:39690001<\/a> PubMed Central PMC11794013<\/a>.<\/li>
  11. Aronson, WJ, Grogan, T, Liang, P, Jardack, P, Liddell, AR, Perez, C et al.<\/i>. High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. J Clin Oncol. 2025;43 (7):800-809. doi: 10.1200\/JCO.24.00608<\/a>. PubMed PMID:39671538<\/a> PubMed Central PMC11869882<\/a>.<\/li>
  12. Kumagai, H, Kim, SJ, Miller, B, Zempo, H, Tanisawa, K, Natsume, T et al.<\/i>. MOTS-c modulates skeletal muscle function by directly binding and activating CK2. iScience. 2024;27 (11):111212. doi: 10.1016\/j.isci.2024.111212<\/a>. PubMed PMID:39559755<\/a> PubMed Central PMC11570452<\/a>.<\/li>
  13. Miller, B, Kim, SJ, Cao, K, Mehta, HH, Thumaty, N, Kumagai, H et al.<\/i>. Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology. Aging Cell. 2024;23 (7):e14153. doi: 10.1111\/acel.14153<\/a>. PubMed PMID:38520065<\/a> PubMed Central PMC11258485<\/a>.<\/li>
  14. Brandhorst, S, Levine, ME, Wei, M, Shelehchi, M, Morgan, TE, Nayak, KS et al.<\/i>. Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk. Nat Commun. 2024;15 (1):1309. doi: 10.1038\/s41467-024-45260-9<\/a>. PubMed PMID:38378685<\/a> PubMed Central PMC10879164<\/a>.<\/li>
  15. Kumagai, H, Kim, SJ, Miller, B, Natsume, T, Wan, J, Kumagai, ME et al.<\/i>. Mitochondrial-derived microprotein MOTS-c attenuates immobilization-induced skeletal muscle atrophy by suppressing lipid infiltration. Am J Physiol Endocrinol Metab. 2024;326 (3):E207-E214. doi: 10.1152\/ajpendo.00285.2023<\/a>. PubMed PMID:38170165<\/a> PubMed Central PMC11196098<\/a>.<\/li>
  16. Kim, SJ, Miller, B, Hartel, NG, Ramirez, R 2nd, Braniff, RG, Leelaprachakul, N et al.<\/i>. A naturally occurring variant of SHLP2 is a protective factor in Parkinson's disease. Mol Psychiatry. 2024;29 (2):505-517. doi: 10.1038\/s41380-023-02344-0<\/a>. PubMed PMID:38167865<\/a> PubMed Central PMC11116102<\/a>.<\/li>
  17. Liang, P, Henning, SM, Grogan, T, Elashoff, D, Said, J, Cohen, P et al.<\/i>. Effect of omega-3 fatty acid diet on prostate cancer progression and cholesterol efflux in tumor-associated macrophages-dependence on GPR120. Prostate Cancer Prostatic Dis. 2024;27 (4):700-708. doi: 10.1038\/s41391-023-00745-4<\/a>. PubMed PMID:37872251<\/a> PubMed Central PMC11035487<\/a>.<\/li>
  18. Hanson, BA, Visvabharathy, L, Orban, ZS, Jimenez, M, Batra, A, Liotta, EM et al.<\/i>. Plasma proteomics show altered inflammatory and mitochondrial proteins in patients with neurologic symptoms of post-acute sequelae of SARS-CoV-2 infection. Brain Behav Immun. 2023;114 :462-474. doi: 10.1016\/j.bbi.2023.08.022<\/a>. PubMed PMID:37704012<\/a> PubMed Central PMC10718560<\/a>.<\/li>
  19. Reams, RR, Odedina, FT, Carpten, JD, Redda, K, Stern, MC, Krieger, JL et al.<\/i>. Florida-California Cancer Research, Education and Engagement (CaRE2<\/sup>) Health Equity Center: Structure, Innovations, and Initial Outcomes. Cancer Control. 2023;30 :10732748231197878. doi: 10.1177\/10732748231197878<\/a>. PubMed PMID:37703814<\/a> PubMed Central PMC10501072<\/a>.<\/li>
  20. Kumagai, H, Miller, B, Kim, SJ, Leelaprachakul, N, Kikuchi, N, Yen, K et al.<\/i>. Novel Insights into Mitochondrial DNA: Mitochondrial Microproteins and mtDNA Variants Modulate Athletic Performance and Age-Related Diseases. Genes (Basel). 2023;14 (2):. doi: 10.3390\/genes14020286<\/a>. PubMed PMID:36833212<\/a> PubMed Central PMC9956216<\/a>.<\/ol>Search PubMed<\/a>[\/vc_column_text][vc_btn title=”Complete Pubmed Search” style=”custom” custom_background=”#0d0f5b” custom_text=”#ffffff” align=”center” css=”” link=”url:https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F%3Fterm%3DCohen%252C%2BPinchas%255BAuthor%255D%26sort%3Ddate|target:_blank”][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

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