Selected Publications
Research
- Hill CM, Albarado DC, Coco LG, Spann RA, Khan MS, Qualls-Creekmore E, Burk DH, Burke SJ, Collier JJ, Yu S, McDougal DH, Berthoud HR, Münzberg H, Bartke A, Morrison CD. FGF21 is required for protein restriction to extend lifespan and improve metabolic health in male mice. Nat Commun. 2022 Apr 7;13(1):1897. PubMed Central PMCID: PMC8991228.
- DuVall MA, Coulter CE, Gosey JL, Herrera MJ, Hill CM, Jariwala RR, Maisano LE, Moldovan LA, Morrison CD, Nwabueze NV, Sikaffy HX, McDougal DH. Leptin treatment prevents impaired hypoglycemic counterregulation induced by exposure to severe caloric restriction or exposure to recurrent hypoglycemia. Auton Neurosci. 2021 Nov;235:102853. PubMed Central PMCID: PMC8532139.
- Fang H, Ghosh S, Sims LC, Stone KP, Hill CM, Spires D, Ilatovskaya DV, Morrison CD, Gettys TW, Stadler K. FGF21 prevents low-protein diet-induced renal inflammation in aged mice. Am J Physiol Renal Physiol. 2021 Sep 1;321(3):F356-F368. PubMed Central PMCID: PMC8530754.
- Jonsson WO, Margolies NS, Mirek ET, Zhang Q, Linden MA, Hill CM, Link C, Bithi N, Zalma B, Levy JL, Pettit AP, Miller JW, Hine C, Morrison CD, Gettys TW, Miller BF, Hamilton KL, Wek RC, Anthony TG. Physiologic Responses to Dietary Sulfur Amino Acid Restriction in Mice Are Influenced by Atf4 Status and Biological Sex. J Nutr. 2021 Apr 8;151(4):785-799. PubMed Central PMCID: PMC8030708.
- Morrison CD, Hill CM, DuVall MA, Coulter CE, Gosey JL, Herrera MJ, Maisano LE, Sikaffy HX, McDougal DH. Consuming a ketogenic diet leads to altered hypoglycemic counter-regulation in mice. J Diabetes Complications. 2020 May;34(5):107557. PubMed Central PMCID: PMC7299499.
- Hill CM, Laeger T, Dehner M, Albarado DC, Clarke B, Wanders D, Burke SJ, Collier JJ, Qualls-Creekmore E, Solon-Biet SM, Simpson SJ, Berthoud HR, Münzberg H, Morrison CD. FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism. Cell Rep. 2019 Jun 4;27(10):2934-2947.e3. PubMed Central PMCID: PMC6579533.
- Allard C, Bonnet F, Xu B, Coons L, Albarado D, Hill C, Fagherazzi G, Korach KS, Levin ER, Lefante J, Morrison C, Mauvais-Jarvis F. Activation of hepatic estrogen receptor-α increases energy expenditure by stimulating the production of fibroblast growth factor 21 in female mice. Mol Metab. 2019 Apr;22:62-70. PubMed Central PMCID: PMC6437689.
- Hill CM, Laeger T, Albarado DC, McDougal DH, Berthoud HR, Münzberg H, Morrison CD. Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints. Sci Rep. 2017 Aug 15;7(1):8209. PubMed Central PMCID: PMC5557875.
- Fang Y, McFadden S, Darcy J, Hill CM, Huber JA, Verhulst S, Kopchick JJ, Miller RA, Sun LY, Bartke A. Differential effects of early-life nutrient restriction in long-lived GHR-KO and normal mice. Geroscience. 2017 Jun;39(3):347-356. PubMed Central PMCID: PMC5505892.
- Hill CM, Fang Y, Miquet JG, Sun LY, Masternak MM, Bartke A. Long-lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high-fat diet on metabolic function and energy expenditure. Aging Cell. 2016 Jun;15(3):509-21. PubMed Central PMCID: PMC4854906.
- Hill CM, Arum O, Boparai RK, Wang F, Fang Y, Sun LY, Masternak MM, Bartke A. Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age. Age (Dordr). 2015 Jun;37(3):9765. PubMed Central PMCID: PMC4424199.
- Fang Y, Westbrook R, Hill C, Boparai RK, Arum O, Spong A, Wang F, Javors MA, Chen J, Sun LY, Bartke A. Duration of rapamycin treatment has differential effects on metabolism in mice. Cell Metab. 2013 Mar 5;17(3):456-62. PubMed Central PMCID: PMC3658445.
Reviews
- Lee MB, Hill CM, Bitto A, Kaeberlein M. Antiaging diets: Separating fact from fiction. Science. 2021 Nov 19;374(6570):eabe7365. PubMed Central PMCID: PMC8841109.
- Hill CM, Qualls-Creekmore E, Berthoud HR, Soto P, Yu S, McDougal DH, Münzberg H, Morrison CD. FGF21 and the Physiological Regulation of Macronutrient Preference. Endocrinology. 2020 Mar 1;161(3). PubMed Central PMCID: PMC7053867.
- Bartke A, Sun L, Fang Y, Hill C. Growth hormone actions during development influence adult phenotype and longevity. Exp Gerontol. 2016 Dec 15;86:22-27. PubMed Central PMCID: PMC4930735.
Career and Educational Development