{"id":145,"date":"2021-02-23T23:55:37","date_gmt":"2021-02-23T23:55:37","guid":{"rendered":"https:\/\/gero.usc.edu\/labs\/longolab\/?page_id=145"},"modified":"2023-07-05T17:44:06","modified_gmt":"2023-07-06T00:44:06","slug":"p01","status":"publish","type":"page","link":"https:\/\/gero.usc.edu\/labs\/longolab\/p01\/","title":{"rendered":"Program Project"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row gap=&#8221;25&#8243;][vc_column width=&#8221;1\/3&#8243;][vc_wp_custommenu nav_menu=&#8221;5&#8243; el_class=&#8221;left-sidebar&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<\/p>\n<div id=\"comp-j22kipdq\" class=\"txtNew\" data-packed=\"true\" data-vertical-text=\"false\">\n<h3 class=\"font_5\">Dietary Restriction, GH\/IGF-1 &amp; Mechanisms of Cellular Protection and Regeneration<\/h3>\n<\/div>\n<div id=\"comp-j01lelz3\" class=\"txtNew\" data-packed=\"false\" data-vertical-text=\"false\" data-min-height=\"155\">\n<p class=\"font_7\">We have brought together biogerontology laboratories from the University of Southern California and Harvard University to study the molecular mechanisms linking fasting, fasting-mimicking diets and protein restriction to growth genes, the stress resistance signaling network, mitochondrial biology, cellular protection, regeneration, and aging. These studies will contribute to the identification of drugs and interventions to treat and prevent multiple diseases by acting on the aging process and on multi-system regeneration and rejuvenation.<\/p>\n<\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_id=&#8221;team-leaders&#8221;][vc_column][vc_column_text]<\/p>\n<h1>Team Leaders<\/h1>\n<p>[\/vc_column_text][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;184&#8243; img_size=&#8221;200&#215;200&#8243; onclick=&#8221;custom_link&#8221; img_link_target=&#8221;_blank&#8221; link=&#8221;https:\/\/gero.usc.edu\/faculty\/longo\/&#8221;][vc_column_text]<\/p>\n<h3><a href=\"http:\/\/gero.usc.edu\/faculty\/longo\/\" target=\"_blank\" rel=\"noopener\">Valter Longo, PhD<\/a><\/h3>\n<p>Professor of Gerontology and Biological Sciences[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;181&#8243; img_size=&#8221;200&#215;200&#8243; onclick=&#8221;custom_link&#8221; img_link_target=&#8221;_blank&#8221; link=&#8221;https:\/\/gero.usc.edu\/faculty\/cohen\/&#8221;][vc_column_text]<\/p>\n<h3><a href=\"http:\/\/gero.usc.edu\/faculty\/cohen\/\">Pinchas Cohen, MD<\/a><\/h3>\n<p>Professor of Gerontology, Medicine and Biological Sciences[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;183&#8243; img_size=&#8221;200&#215;200&#8243; onclick=&#8221;custom_link&#8221; img_link_target=&#8221;_blank&#8221; link=&#8221;https:\/\/gero.usc.edu\/faculty\/brandhorst\/&#8221;][vc_column_text]<\/p>\n<h3><a href=\"https:\/\/gero.usc.edu\/faculty\/sebastian-brandhorst-phd\/\" target=\"_blank\" rel=\"noopener\">Sebastian Brandhorst, PhD<\/a><\/h3>\n<p>Research Assistant Professor of Gerontology[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;182&#8243; img_size=&#8221;200&#215;200&#8243; onclick=&#8221;custom_link&#8221; img_link_target=&#8221;_blank&#8221; link=&#8221;https:\/\/gero.usc.edu\/faculty\/cohen\/&#8221;][vc_column_text]<\/p>\n<h3><a href=\"https:\/\/ludwigcancer.princeton.edu\/people\/sarah-mitchell\">Sarah Jayne Mitchell, PhD<\/a><\/h3>\n<p>Staff Scientist[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row gap=&#8221;25&#8243;][vc_column width=&#8221;1\/3&#8243;][vc_wp_custommenu nav_menu=&#8221;5&#8243; el_class=&#8221;left-sidebar&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text] Dietary Restriction, GH\/IGF-1 &amp; Mechanisms of Cellular Protection and Regeneration We have brought together biogerontology laboratories from the University of Southern California and Harvard University to study the molecular mechanisms linking fasting, fasting-mimicking diets and protein restriction to growth genes, the stress resistance signaling network, mitochondrial biology, cellular protection, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-full.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-145","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Program Project - The Longo Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/gero.usc.edu\/labs\/longolab\/p01\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Program Project - The Longo Lab\" \/>\n<meta property=\"og:description\" content=\"[vc_row gap=&#8221;25&#8243;][vc_column width=&#8221;1\/3&#8243;][vc_wp_custommenu nav_menu=&#8221;5&#8243; el_class=&#8221;left-sidebar&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text] Dietary Restriction, GH\/IGF-1 &amp; Mechanisms of Cellular Protection and Regeneration We have brought together biogerontology laboratories from the University of Southern California and Harvard University to study the molecular mechanisms linking fasting, fasting-mimicking diets and protein restriction to growth genes, the stress resistance signaling network, mitochondrial biology, cellular protection, [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/gero.usc.edu\/labs\/longolab\/p01\/\" \/>\n<meta property=\"og:site_name\" content=\"The Longo Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2023-07-06T00:44:06+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/p01\\\/\",\"url\":\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/p01\\\/\",\"name\":\"Program Project - The Longo Lab\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/#website\"},\"datePublished\":\"2021-02-23T23:55:37+00:00\",\"dateModified\":\"2023-07-06T00:44:06+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/p01\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/p01\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/p01\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Program Project\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/#website\",\"url\":\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/\",\"name\":\"The Longo Lab\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/gero.usc.edu\\\/labs\\\/longolab\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Program Project - The Longo Lab","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/gero.usc.edu\/labs\/longolab\/p01\/","og_locale":"en_US","og_type":"article","og_title":"Program Project - The Longo Lab","og_description":"[vc_row gap=&#8221;25&#8243;][vc_column width=&#8221;1\/3&#8243;][vc_wp_custommenu nav_menu=&#8221;5&#8243; el_class=&#8221;left-sidebar&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text] Dietary Restriction, GH\/IGF-1 &amp; Mechanisms of Cellular Protection and Regeneration We have brought together biogerontology laboratories from the University of Southern California and Harvard University to study the molecular mechanisms linking fasting, fasting-mimicking diets and protein restriction to growth genes, the stress resistance signaling network, mitochondrial biology, cellular protection, [&hellip;]","og_url":"https:\/\/gero.usc.edu\/labs\/longolab\/p01\/","og_site_name":"The Longo Lab","article_modified_time":"2023-07-06T00:44:06+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/gero.usc.edu\/labs\/longolab\/p01\/","url":"https:\/\/gero.usc.edu\/labs\/longolab\/p01\/","name":"Program Project - The Longo Lab","isPartOf":{"@id":"https:\/\/gero.usc.edu\/labs\/longolab\/#website"},"datePublished":"2021-02-23T23:55:37+00:00","dateModified":"2023-07-06T00:44:06+00:00","breadcrumb":{"@id":"https:\/\/gero.usc.edu\/labs\/longolab\/p01\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/gero.usc.edu\/labs\/longolab\/p01\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/gero.usc.edu\/labs\/longolab\/p01\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/gero.usc.edu\/labs\/longolab\/"},{"@type":"ListItem","position":2,"name":"Program Project"}]},{"@type":"WebSite","@id":"https:\/\/gero.usc.edu\/labs\/longolab\/#website","url":"https:\/\/gero.usc.edu\/labs\/longolab\/","name":"The Longo Lab","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/gero.usc.edu\/labs\/longolab\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/gero.usc.edu\/labs\/longolab\/wp-json\/wp\/v2\/pages\/145","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gero.usc.edu\/labs\/longolab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/gero.usc.edu\/labs\/longolab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/gero.usc.edu\/labs\/longolab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gero.usc.edu\/labs\/longolab\/wp-json\/wp\/v2\/comments?post=145"}],"version-history":[{"count":0,"href":"https:\/\/gero.usc.edu\/labs\/longolab\/wp-json\/wp\/v2\/pages\/145\/revisions"}],"wp:attachment":[{"href":"https:\/\/gero.usc.edu\/labs\/longolab\/wp-json\/wp\/v2\/media?parent=145"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}