It is well recognized that intermittent fasting and time restricted feeding can improve health incl. treatment of metabolic syndrome, but there had not been many studies done on the mechanism behind the anticancer effect of time restricted feeding or intermittent fasting. The findings in this paper suggest that fasting from dawn to sunset can be an effective treatment for metabolic syndrome and prevention of cancer in humans.
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3 Cycles of Fasting-Mimicking Diet Indicate a 2.5 Years Reduction in Biological Age, Leading to Healthier Metabolic Biomarkers and Longer Healthspan.
The fasting-mimicking diet (FMD) is a plant-based, 5-day dietary intervention designed to emulate fasting benefits while minimizing negative side effects. Developed by Dr. Valter Longo and his team, recent clinical trials show FMD can lower biological age by 2.5 years, enhance insulin sensitivity and reduce liver fat, making it a promising strategy for improving healthspan and combating chronic diseases.

Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries
One of the problems when it comes to a person getting older is the progressive frailty that accompanies them later in life. Frailty from aging results in issues involving the failure of various physiological functions and systems, including but not limited to the development of

Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Benefits both Health Span and Lifespan
Elevated oxidative stress and mitochondrial dysfunction are key factors in biological aging. Glutathione (GSH), the body's most abundant intracellular antioxidant, plays a critical role in protecting mitochondria from oxidative damage. This double-blind randomized clinical trial explored the effects of GlyNAC supplementation—a combination of glycine and N-acetylcysteine, both GSH precursors—on older adults.

USC Leonard Davis School Faculty Win Grants to Explore New Ways to Improve Health
USC Leonard Davis School of Gerontology announces that Longevity Institute’s Kelvin Yen was awarded the 2017 Hanson-Thorell Family Research Scholarship.
USC Leonard Davis School Innovators Honored by USC Stevens Center
USC Leonard Davis School of Gerontology announced that the USC Stevens Center awarded Longevity Institute’s Valter Longo. “We are very happy to have been able to make a series of discoveries that resulted in issued patents, particularly since they represent some of the first patents related
Pinchas Cohen is on the panel, “Will You Live to a Healthy 100,” at the Milken Institute 2017 Global Conference
This Milken Institute panel explored the pioneering discoveries bringing us closer to healthy aging.
Grand Challenges: Aging @ Nature Podcast
Longevity Institute’s Sean Curran discusses the aging process and the major challenges to be solved so we can live healthily and well on Nature Podcast.
Eileen Crimmins signs National Academy of Sciences registry of membership
The National Academy of Sciences presented Longevity Institute’s Eileen Crimmins as a member in 2017.