ARCO/William F. Kieschnick Professor of the Neurobiology of Aging University Professor
PhD, Rockefeller University, 1969
BS, Yale, 1961
Basic mechanisms in the human biology of aging, with focus on inflammation and nutritional influences
Air pollution influences on aging
Evolution of the human lifespan and diseases of aging, especially Alzheimer disease
Caleb Finch’s major research interest is the study of basic mechanisms in human aging with a focus on inflammation. He has received most of the major awards in biomedical gerontology, including the Robert W. Kleemeier Award of the Gerontological Society of America in 1985, the Sandoz Premier Prize by the International Geriatric Association in 1995, and the Irving Wright Award of AFAR and the Research Award of AGE in 1999. He was the founder of the NIA-funded Alzheimer Disease Research Center in 1984 and currently serves as co-Director. Finch became a University Distinguished Professor in 1989, an honor held by sixteen other professors at USC who contribute to multiple fields. He is a member of five editorial boards and has written four books and 475 articles. A new research area is the effect of air pollution on brain development and aging, which he is developing through a USC-wide network (AirPollBrain website http://envneurosci.usc.edu/APB)
Bisc 510a Integrative and Evolutionary Biology (a: 4, Fa; b: 4, Sp) Current topics in integrative and evolutionary biology including genetics, natural selection, ecology with emphasis on higher order complex questions including form, function, and energy use throughout the life span.
Bisc 549b Seminar in Integrative and Evolutionary Biology (2, max 6, FaSp) Current topics in integrative and evolutionary biology.
Gero 416 Health Issues in Aging (4, Sp) Physiological, psychological, and social health problems of older people; organizational factors in health care delivery.
Mazumder B, Almond D, Park K, Crimmins EM, Finch CE (2010)Lingering prenatal effects of the 1918 Influenza Pandemic on cardiovascular disease. J Devel Origins Health Dis 1:26-34.
Finch CE (2012) The evolution of the human lifespan, past present and future. Trans Am Philosoph Soc 156: 9-44
Davis DA, Akopian G, Walsh JP, Sioutas C, Morgan TE, Finch CE. (2013) Urban air pollutants reduce synaptic function of CA1 neurons via an NMDA/NO pathway in vitro. J Neurochem 127:509-519
Finch CE, Beltran-Sanchez H, Crimmins EM (2014) Uneven futures of human lifespans: reckoning the realities of climate change with predictions from the Gompertz model. Gerontology 60:183-8.
Thompson RC, Allam AH, Zink A, Wann LS, Lombardi GP, Cox SL, Frohlich B, Sutherland ML, Sutherland JD, Frohlich T, King, S I, Miyamoto MI, Monge JM, Vallodolid CM, Nur el-din AH, Narula J, Finch CE, Thomas GS. CT evidence of atherosclerosis in the mummified remains of humans from around the world. Global Heart J, in press.