Aging Biomarker and Service Core

Services

• Inflammatory cytokines/chemokines
• Alzheimer-related markers (Amyloid beta, phospho-tau)
• Metabolic biomarkers (insulin, leptin, adiponectin, etc)
• Human and mouse IGF-I & IGFBPs (1, 2 3), GH, etc.,
• Mitochondrial derived peptides (MDPs): humanin, SHLP2, MOTS- C, etc
• New assay development

Platforms

Meso Scale Discovery system (MSD)

• ~10 analytes small
• small sample volume (10-25 µL)
• high sensitivity
• broad dynamic range

SpectraMax M3 multi-mode microplate reader:

• absorbance, fluorescence, luminescence)
• Application: ELISA, cell viability, fluorescent protein detection