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Jessica Ho Portrait

Assistant Professor Jessica Ho

The ongoing opioid epidemic in the United States is one of the key contributors to the most recent declines in life expectancy, suggests a USC-led study.

The study, authored by USC Leonard Davis School of Gerontology Assistant Professor Jessica Ho and Arun Hendi of Princeton University, looked at trends in life expectancy across 18 high-income countries and found that most countries experienced declines in life expectancy in 2015. The findings point to an urgent need to examine systemic causes of declining life expectancy in the US.

Life expectancy is a measure of the health and wellbeing of a population. Widespread or sustained declines in life expectancy may signal problems in a nation’s social and economic conditions or in the provision or quality of its healthcare services.

This is the first time in recent decades that these many high-income countries simultaneously experienced declines in life expectancy for both men and women, and the size of these declines were larger than in the past.

In the non-US countries, these declines were largely concentrated at ages 65 and older and likely related to a particularly severe influenza season. The main causes of death driving these declines included influenza and pneumonia, respiratory disease, cardiovascular disease, and Alzheimer’s disease and other mental and nervous system disorders.

But in the US, the decline was concentrated at younger ages, particularly those in their 20s and 30s, and largely driven by increases in drug overdose deaths related to its ongoing opioid epidemic. The authors point out that the US decline is particularly troubling in light of its already low life expectancy ranking relative to its peer countries.

“In the US, we tend to die at younger ages, particularly from causes of death like drug overdose and motor vehicle accidents, and we also have higher infant mortality than other rich nations,” Ho said. She added that large inequalities in life expectancy by socioeconomic status exist in the US, and life expectancy trends for Americans of lower socioeconomic status have been particularly adverse in recent years.

And unlike other countries in the study, life expectancy in both the US and the UK continued to decline in 2016, which the researchers say raises questions about future trends in these countries.

“These factors can change in a short period of time—a decade ago, drug overdose mortality didn’t have a strong influence on American life expectancy, but now its imprint is growing,” Ho said. “In general, life expectancy in the US is increasing much more slowly than in other high-income countries, and we’re failing to keep pace with our peer countries.”

The article, “Recent trends in life expectancy across high income countries: retrospective observational study,” was published in The BMJ on August 15, 2018. Principal support for this research was provided by a grant from the Robert Wood Johnson Foundation (74439). Ho is supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health (award R00HD083519), and Hendi is supported by a pilot grant from the National Institute on Aging of the National Institutes of Health (award P30AG043073).

Release courtesy of The BMJ; additional material by Beth Newcomb. Top illustration: Shutterstock/Arthimedes.

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