Transposons, genes that can relocate to different parts of the genome, are repressed earlier in life but get more active with age and are associated with age-related disease and decline.
Mycothiazole and its synthetic derivative target the mitochondria’s electron transport chain and show targeted toxicity against human cancer cells as well as anti-aging properties in worms.
Patients who received brochures about risks, alternatives, and tapering recommendations were more likely to successfully quit taking benzodiazepine medications, drugs which pose particularly high risks for older adults.
Findings suggest the rare variant prevents Alzheimer’s onset by clearing away amyloid-beta buildup in long-lived carriers of APOE4, the gene most strongly associated with disease risk.
USC study shows how cycles of a fasting-mimicking diet reduce insulin resistance, liver fat, immune system aging, and biological age in clinical trial patients.
Medical texts from 2,500 years ago rarely mention severe memory loss, suggesting today’s widespread dementia stems from modern environments and lifestyles, a new USC analysis shows.
The Gerontology Enriching Medicine, Science, Technology, Engineering and Mathematics (GEMSTEM) to Enhance Diversity in Aging program supports the next generation of gerontology researchers.