How a serendipitous discovery more than 20 years ago led to a new chapter in biology and made the USC Leonard Davis School a leading force in unraveling the mysteries of mitochondria.
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Findings suggest the rare variant prevents Alzheimer’s onset by clearing away amyloid-beta buildup in long-lived carriers of APOE4, the gene most strongly associated with disease risk.
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Beneficial variant is a mitochondrial microprotein that could be key to developing future pharmaceutical interventions.
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A mutation in the small protein SHMOOSE is associated with Alzheimer’s risk and highlights a possible target for treatment.
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Study suggests changes in strength and mobility may depend on genetic variations in a critical mitochondrial enzyme.
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The USC Daryl and Irwin Simon Nutrition for Alzheimer’s Disease Prevention Research Fund was created to explore the role diet can play in the prevention or delay of Alzheimer’s disease.
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Mitochondrial peptide MOTS-c regulates the immune system and prevents the self-destruction of cells that create insulin, according to a new study in mice.
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Here’s just some of what we’ve learned by listening to Lessons in Lifespan Health, the podcast produced by the USC Leonard Davis School of Gerontology.
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Researchers also identify molecular pathway that can inform development of treatments for muscle-wasting conditions such as sarcopenia.
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During moderate exercise, the brain’s hypothalamus – the region controlling metabolism – releases a hormone linked to obesity resistance, according to research in mice.
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